62600-73-1

Basic information

• Product Name: (R)-(4-Methoxyphenyl)oxirane
• Synonyms: (R)-(4-METHOXYPHENYL)OXIRANE;(R)-4-Methoxystyreneoxide;(R)-2-(4-methoxyphenyl)oxirane;(2R)-2-(4-methoxyphenyl)oxirane
• CAS NO: 62600-73-1
• Molecular Formula: C₉H₁₀O₂
• Molecular Weight: 150.17
• Mol File: 62600-73-1.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 244.7 °C at 760 mmHg
• Flash Point: 101.2 °C
• Appearance: /
• Density: 1.133g/cm³
• Refractive Index: 1.546
• CAS DataBase Reference: (R)-(4-Methoxyphenyl)oxirane(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(4-Methoxyphenyl)oxirane(62600-73-1)
• EPA Substance Registry System: (R)-(4-Methoxyphenyl)oxirane(62600-73-1)

Safety Data

• Hazardous Substances Data: 62600-73-1(Hazardous Substances Data)

Usage

General Description

(R)-(4-Methoxyphenyl)oxirane, also known as (R)-1,2-epoxy-4-methoxybenzene, is a chemical compound with the molecular formula C9H10O2. It is a colorless liquid with a faint, sweet odor. (R)-(4-Methoxyphenyl)oxirane is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and fragrances. It is also utilized in the production of polymers, resins, and fine chemicals. (R)-(4-Methoxyphenyl)oxirane is a chiral compound, meaning it has a non-superposable mirror image, often referred to as (S)-(4-Methoxyphenyl)oxirane. This chemical is considered to be hazardous and should be handled with care in a controlled laboratory setting.

InChI:InChI=1/C9H10O2/c1-10-8-4-2-7(3-5-8)9-6-11-9/h2-5,9H,6H2,1H3/t9-/m0/s1

Upstream product

• 637-69-4 4-Methoxystyrene 
• 117465-37-9 (R)?2?bromo?1?(4′?methoxyphenyl)ethanol 
• 123-11-5 4-methoxy-benzaldehyde 
• 111324-03-9 1-tert-butyl-2,2,4,4,4-pentakis(dimethylamino)-2Λ⁵,4Λ⁵-catenadi(phosphazene) 
• 1190369-08-4 n-butyl (2R)-2-hydroxy-2-(p-methoxyphenyl)-ethyl (R)-sulfoxide 
• 2632-13-5 2-Bromo-4'-methoxyacetophenone 
• 117340-79-1 2-bromo-1-(4-methoxyphenyl)ethanol 
• 13603-63-9 (R)-1-(4-methoxyphenyl)ethane-1,2-diol 

Downstream Products

• 1613041-16-9 (3R,5S)-5-(4-methoxyphenyl)-3-methyltetrahydro-2H-pyran-2-one 
• 1613041-17-0 (3S,5S)-5-(4-methoxyphenyl)-3-methyltetrahydro-2H-pyran-2-one 
• 1613041-18-1 (3R,4S)-3-ethyl-4-(4-methoxyphenyl)dihydrofuran-2(3H)-one 
• 1613041-19-2 (3S,4S)-3-ethyl-4-(4-methoxyphenyl)dihydrofuran-2(3H)-one 
• 1613040-95-1 (S,Z)-2-(4-methoxyphenyl)pent-3-en-1-ol 
• 1402850-41-2 N-(4-(4-methoxyphenyl)-3-phenyl-4,5-dihydrofuran-2-yl)-N-methylmethanesulfonamide 
• 1517-70-0 (S)-1-(4-Methoxyphenyl)ethanol 
• 1644034-05-8 (R)-methyl 5-(4-methoxyphenyl)-3-methyl-5,6-dihydro-1,4-dioxine-2-carboxylate 

Relevant articles and documents

Asymmetric synthesis of α-bromohydrins by carrot root as biocatalyst and conversion to enantiopure β-hydroxytriazoles and styrene oxides using click chemistry and SN2 ring-closure

In this study we have combined the bioreduction of α-bromoketones using carrot root as biocatalyst and click chemistry for the preparation of enantiopure β-hydroxytriazoles in excellent enantiomeric excesses and yields. Moreover, we have utilized chiral α-halohydrins for the synthesis of enantiopure styrene oxides in very good yields and enantiomeric excesses. Structural assignments of the products were based on their 1H and 13C NMR data and their optical rotations. The enantiomeric excess of the chiral products was obtained by HPLC analysis.

Highly enantioselective ylide-mediated synthesis of terminal epoxides

The highly efficient asymmetric epoxidation of aldehydes by methylene transfer is now possible using new sulfonium salts. This journal is

Enantioselective synthesis of phenyl-ethanolamines through application of chiral sulfoxide

Efficient enantioselective synthesis of (R)- and (S)-enantiomers of 2-(tert-butylamino)-1-(p-methoxyphenyl)-ethanol has been achieved in high enantiomeric excess by using asymmetric sulfoxide as a chiral auxiliary. The present synthetic approach was further extended to the asymmetric synthesis of (R)-salbutamol. Copyright Taylor & Francis Group, LLC.