6273-94-5Relevant articles and documents
A novel C-C bond formation by Baylis-Hillman type reaction mediated by SmI2: An effective approach to α-hydroxyalkylacrylamide synthesis
Youn,Park,Kim
, p. 2005 - 2006 (2000)
α-Bromoacrylamides (1) reacted with aldehydes or ketones, in the presence of SmI2 at - 78 °C in THF, within 5 min to produce Baylis-Hillman type reaction products (2) through an anionic process using vinylsamarium Grignard species in good yield
Synthesis of Phenanthridine and Quinoxaline Derivatives via Copper-Catalyzed Radical Cyanoalkylation of Cyclobutanone Oxime Esters and Vinyl Azides
Kong, Xianqiang,Li, Guodong,Liang, Qi,Lin, Long,Xu, Bo
supporting information, p. 1948 - 1952 (2021/06/09)
A copper-catalyzed radical cyclization of cyclobutanone oxime esters and vinyl azide is described. This method provides facile access to cyanoalkyl-substituted phenanthridines and quinoxalines with excellent isolated yields. Moreover, these reactions proceed under mild conditions with a board substrate scope and excellent functional group tolerance.
An efficient approach for the synthesis of new (±)-coixspirolactams
Nascimento, Vinicius R.,Suenaga, Melissa L. S.,Andrade, Leandro H.
, p. 5458 - 5465 (2020/08/03)
Coixspirolactams, spiro[oxindole-γ-lactones], are found in adlay seeds and exhibit anticancer activity. A novel synthetic methodology was developed to enable an easy access to (±)-coixspirolactam A and a large number of new coixspirolactams in excellent overall yields. The exquisite exploitation of formamide reactivity was essential for the construction of oxindole and lactone scaffolds. This journal is
