6288-76-2 Usage
Description
(5Z)-5-(3-methylcyclohexylidene)-2-thioxoimidazolidin-4-one, commonly known as thiazolidinedione, is a chemical compound characterized by a five-membered heterocyclic ring that includes a sulfur atom. It is recognized for its role in the management of type 2 diabetes, where it functions to decrease blood sugar levels by enhancing the sensitivity of peripheral tissues to insulin.
Uses
Used in Pharmaceutical Industry:
(5Z)-5-(3-methylcyclohexylidene)-2-thioxoimidazolidin-4-one is used as an antidiabetic medication for managing type 2 diabetes. It operates by activating peroxisome proliferator-activated receptor gamma (PPAR-γ) within the cell nucleus, which in turn regulates gene expression that is pivotal for glucose and lipid metabolism. This action helps in the reduction of blood sugar levels, offering a therapeutic benefit for patients with type 2 diabetes.
However, the use of thiazolidinedione in this capacity is accompanied by potential side effects such as weight gain, fluid retention, and an increased risk of heart failure. Despite these concerns, it continues to be an important therapeutic option due to its effectiveness in treating type 2 diabetes.
Check Digit Verification of cas no
The CAS Registry Mumber 6288-76-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,8 and 8 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 6288-76:
(6*6)+(5*2)+(4*8)+(3*8)+(2*7)+(1*6)=122
122 % 10 = 2
So 6288-76-2 is a valid CAS Registry Number.