62961-57-3Relevant articles and documents
HIGHLY STEREOSELECTIVE PROCEDURE FOR (6R)-TETRAHYDROBIOPTERIN COFACTOR
Matsuura, Sadao,Murata, Shizuaki,Sugimoto, Takashi
, p. 735 - 738 (1984)
(6R)-Tetrahydrobiopterin cofactor for aromatic amino acid hydroxylases was synthesized stereoselectively by catalytic hydrogenation of biopterin over platinum oxide at pH 11.4 and subsequent crystallization from hydrochloric acid and ethanol.
HYDROGENATION OF BIOPTERIN AND ITS ANALOGUES; APPLICATION FOR THE CONVENIENT PROCEDURE OF BIOPTERIN COFACTOR AND RELATED 5,6,7,8-TETRAHYDROPTERINS
Matsuura, Sadao,Murata, Shizuaki,Sugimoto, Takashi
, p. 3115 - 3120 (2007/10/02)
A large scale and stereoselective hydrogenation of biopterin to (6R)-5,6,7,8-tetrahydrobiopterin was developed.The procedure was applied for various hydroxyalkylpterins such as neopterin and diastereomers of biopterin.