6306-97-4

Basic information

• Product Name: 1,3-bis(4-methoxyphenyl)isobenzofuran
• Synonyms: 1,3-bis(4-methoxyphenyl)isobenzofuran
• CAS NO: 6306-97-4
• Molecular Formula: C₂₂H₁₈O₃
• Molecular Weight: 330.38
• Mol File: 6306-97-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 498.1°C at 760 mmHg
• Flash Point: 265.8°C
• Appearance: /
• Density: 1.159g/cm³
• Vapor Pressure: 1.44E-09mmHg at 25°C
• Refractive Index: 1.611
• CAS DataBase Reference: 1,3-bis(4-methoxyphenyl)isobenzofuran(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-bis(4-methoxyphenyl)isobenzofuran(6306-97-4)
• EPA Substance Registry System: 1,3-bis(4-methoxyphenyl)isobenzofuran(6306-97-4)

Safety Data

• Hazardous Substances Data: 6306-97-4(Hazardous Substances Data)

Usage

Class

Isobenzofuran derivatives

Core structure

Isobenzofuran

Substituents

Two 4-methoxyphenyl groups

Attachment positions

1 and 3

Potential applications

a. Photochemical reagent
b. Scaffold for drug design

Biological activities

Studied for potential applications

Research and development

Valuable for pharmaceutical and material science industries

Unique structure

Contributes to its properties and potential uses

InChI:InChI=1/C22H18O3/c1-23-17-11-7-15(8-12-17)21-19-5-3-4-6-20(19)22(25-21)16-9-13-18(24-2)14-10-16/h3-14H,1-2H3

Upstream product

• 7664-93-9 sulfuric acid 
• 7477-32-9 acide (dimethoxy-4'4 diphenylmethyl)-2 benzoique 
• 4122-56-9 methyl o-formylbenzoate 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 655-63-0 2-(dibromomethyl)benzonitrile 
• 529-19-1 2-Methylbenzonitrile 
• 15331-49-4 trans-1,2-di(4-methoxybenzoyl)ethylene 
• 4122-57-0 3-methoxy-3H-isobenzofuran-1-one 
• 7719-09-7 thionyl chloride 
• 71-43-2 benzene 
• 74322-73-9 [2-Diethylamino-6-(4-methoxy-benzoyl)-cyclohex-3-enyl]-(4-methoxy-phenyl)-methanone 
• 7468-67-9 o-formylbenzonitrile 
• 108-24-7 acetic anhydride 
• 5435-44-9 (E)-3-Ureido-but-2-enoic acid ethyl ester 

Downstream Products

• 87771-75-3 9,14-di-(4'-methoxyphenyl)dibenzanthracene 
• 1170321-13-7 1,4-bis-(4-methoxyphenyl)naphthalene 
• 1610619-49-2 6,11-bis(4-methoxyphenyl)benzo[b]naphtho[2,3-d]thiophene S,S-dioxide 
• 1610619-51-6 5,13-bis(4-methoxyphenyl)dinaphtho[2,3-b:2',3'-d]thiophene S,S-dioxide 
• 1610619-86-7 C₇₂H₆₅NO₈S₂ 
• 1610619-79-8 C₇₈H₈₆O₁₀S₂ 
• 1610619-75-4 C₆₆H₆₂O₁₀S₂ 
• 1610619-89-0 C₂₇H₂₂O₃ 
• 1610619-69-6 5,6,11,13-tetrakis(4-methoxyphenyl)-12H-dibenzo[b,h]fluoren-12-one 
• 1610619-66-3 5,13-bis(4-methoxyphenyl)-6,11-diphenyl-12H-dibenzo[b,h]fluoren-12-one 
• 1054569-40-2 1,3-bis(4-methoxyphenyl)benzo[c]selenophene 
• 7477-30-7 1,2-bis-(α-hydroxyimino-4-methoxy-benzyl)-benzene 
• 860531-53-9 2-methoxy-9-(4-methoxyphenyl)anthracene 
• 855422-65-0 1,2-bis-(4-hydroxy-benzoyl)-benzene 

Relevant articles and documents

A One-pot preparation of 1,3-diarylisobenzofuran

A simple, practical, and efficient method for one-pot synthesis of symmetric and unsymmetrical 1,3-diarylisobenzofurans has been developed by sequential reactions of methyl 2-formylbenzoate with two identical or different aryl metal species.

A single-step synthesis of symmetrical 1,3-diarylisobenzofurans

A convenient single-step synthesis of various symmetrically substituted 1,3-diarylisobenzofurans from readily available 3-methoxy-3H-isobenzofuran-1-one (1a) and two equivalents of aryl Grignard reagents is described. The title compounds are obtained in medium to high isolated yields. Crude isobenzofuran has also been trapped by maleimide, furnishing pure Diels-Alder adduct almost quantitatively. Georg Thieme Verlag Stuttgart.