655-63-0 Usage
Description
α,α-Dibromo-o-tolunitrile, also known as 2-Dibromomethyl-benzonitrile, is an organic compound that is primarily recognized as an impurity in the production of Alogliptin (A575425). Alogliptin is an oral antihyperglycemic agent that functions as a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4), playing a significant role in the management of type 2 diabetes.
Uses
Used in Pharmaceutical Industry:
α,α-Dibromo-o-tolunitrile is used as an impurity in the production of Alogliptin, an oral antihyperglycemic agent, for the management of type 2 diabetes. Its presence, although as an impurity, is significant in the pharmaceutical industry due to its association with the production of a drug that helps regulate blood sugar levels in diabetic patients.
As an Antidiabetic Agent:
While α,α-Dibromo-o-tolunitrile itself may not have direct applications as an antidiabetic agent, its connection to Alogliptin, a selective DPP-4 inhibitor, highlights its importance in the development and production of medications aimed at treating type 2 diabetes. DPP-4 inhibitors like Alogliptin work by increasing the levels of insulin-producing hormones, thus helping to lower blood sugar levels in patients with diabetes.
Check Digit Verification of cas no
The CAS Registry Mumber 655-63-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,5 and 5 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 655-63:
(5*6)+(4*5)+(3*5)+(2*6)+(1*3)=80
80 % 10 = 0
So 655-63-0 is a valid CAS Registry Number.
655-63-0Relevant articles and documents
Cascade Skeletal Rearrangement of Gold Carbene Intermediates: Synthesis of Medium-Sized Pyrimidine-Fused Benzolactones
Hu, Xiaoping,Liu, Yuanhong,Wang, Ali,Xie, Xin
supporting information, p. 3769 - 3774 (2021/07/17)
A gold-catalyzed cyclization/cascade skeletal rearrangement of o-cyanophenylalkynones with 3-amino-benzo[d]-isoxazoles has been developed, which provides an approach for synthesizing medium-sized benzolactones. Based on the experimental results, we postul
