63193-70-4

Basic information

• Product Name: Benzoyl isothiocyanate, 4-(dimethylamino)-
• CAS NO: 63193-70-4
• Molecular Formula: C10H10N2OS
• Molecular Weight: 206.268
• Mol File: 63193-70-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzoyl isothiocyanate, 4-(dimethylamino)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoyl isothiocyanate, 4-(dimethylamino)-(63193-70-4)
• EPA Substance Registry System: Benzoyl isothiocyanate, 4-(dimethylamino)-(63193-70-4)

Safety Data

• Hazardous Substances Data: 63193-70-4(Hazardous Substances Data)

Upstream product

• 4755-50-4 4-(dimethylamino)benzoyl chloride 
• 1147550-11-5 ammonium thiocyanate 
• 592-87-0 lead(II) thiocyanate 

Downstream Products

• 1186137-90-5 C₂₉H₃₂ClN₃O₃S 
• 1448365-70-5 11β-(4-dimethylaminobenzoyloxy)-15β-hydroxykaur-16-en-19-oic acid 
• 1442093-69-7 (R)-4-(dimethylamino)-N-(1-hydroxybutan-2-ylcarbamothioyl)benzamide 
• 859734-86-4 4-dimethylamino-N-[(4-ethoxy-phenyl)-thiocarbamoyl]-benzamide 

Relevant articles and documents

Efficient synthesis of new (R)-2-amino-1-butanol derived ureas, thioureas and acylthioureas and in vitro evaluation of their antimycobacterial activity

The synthesis of 22 structurally diverse urea, thiourea and acylthiourea derivatives containing the (R)-2-amino-1-butanol motif has been performed. The evaluation of their in vitro activity against Mycobacterium tuberculosis (H 37Rv and strain

Intramolecular hydrogen bonding and anion binding of N-benzamido-N′- benzoylthioureas

(Chemical Equation Presented) N-(p-Dimethylamino)benzoyl-N′- phenylthiourea as an N-acylthiourea is known to be unable to bind anions due to a strong intramolecular hydrogen bond (IHB). We show here that by inserting an amido group in the N′-phenyl side the newly designed N-benzamido-N′- benzoylthioureas, despite this IHB too, bind strongly to anions with binding constants on the order of 106-107 mol-1 L. Results suggest that potential anion receptors or organocatalysts could be developed on the basis of this framework with a wide structural diversity.