632-46-2Relevant articles and documents
Treffers,Hammett
, p. 1708,1709 (1937)
Magnesiation of Aryl Fluorides Catalyzed by a Rhodium-Aluminum Complex
Fujii, Ikuya,Semba, Kazuhiko,Li, Qiao-Zhi,Sakaki, Shigeyoshi,Nakao, Yoshiaki
supporting information, p. 11647 - 11652 (2020/08/06)
We report the magnesiation of aryl fluorides catalyzed by an Al-Rh heterobimetallic complex. We show that the complex is highly reactive to cleave the C-F bonds across the polarized Al-Rh bond under mild conditions. The reaction allows the use of an easy-to-handle magnesium powder to generate a range of arylmagnesium reagents from aryl fluorides, which are conventionally inert to such metalation compared with other aryl halides.
Nickel-Catalyzed Ortho C–H Methylation of Aromatic Amides with Di-tert-butyl Peroxide as Methylation Reagent
Liu, Da,Yu, Lin,Yu, Yongqi,Xia, Zhen,Song, Zenan,Liao, Lihong,Tan, Ze,Chen, Xiang
supporting information, p. 6930 - 6934 (2019/11/13)
A new efficient protocol for the ortho-methylation of benzamides with DTBP has been developed via Ni(II)-catalyzed C–H activation directed by 8-aminoquinoline. This method is performed under base-free, ligand-free conditions and utilizes cheap and commercially available reagents. Moreover, the by-product acetone derived from DTBP does not affect the purification of the product.