2211-84-9

Basic information

• Product Name: 7-Methyl Phthalide
• Synonyms: 7-Methyl Phthalide;7-Methylisobenzofuran-1(3H)-one;7-methyl-3H-2-benzofuran-1-one
• CAS NO: 2211-84-9
• Molecular Formula: C₉H₈O₂
• Molecular Weight: 148.15862
• Mol File: 2211-84-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 326.6°C at 760 mmHg
• Flash Point: 134.9°C
• Appearance: /
• Density: 1.211g/cm³
• Vapor Pressure: 0.000213mmHg at 25°C
• Refractive Index: 1.574
• CAS DataBase Reference: 7-Methyl Phthalide(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Methyl Phthalide(2211-84-9)
• EPA Substance Registry System: 7-Methyl Phthalide(2211-84-9)

Safety Data

• Hazardous Substances Data: 2211-84-9(Hazardous Substances Data)

Usage

General Description

7-Methyl phthalide is a chemical compound with a unique odor and flavor profile often described as sweet, woody, and nutty. It is found in certain fruits and vegetables, and is a common aroma and flavor component in foods and beverages. 7-Methyl Phthalide may also have potential health benefits, as it has been studied for its antioxidative, anti-inflammatory, and neuroprotective properties. Additionally, 7-methyl phthalide has been investigated for potential therapeutic use in the treatment of various health conditions, including cancer and neurodegenerative diseases. Overall, 7-methyl phthalide is a versatile chemical with diverse applications in the food industry and potential pharmaceutical uses.

InChI:InChI=1/C9H8O2/c1-6-3-2-4-7-5-11-9(10)8(6)7/h2-4H,5H2,1H3

Upstream product

• 632-46-2 2,6-dimethylbenzoic acid 
• 4792-30-7 3-methylphthalic acid anhydride 
• 90534-48-8 2-(hydroxymethyl)-3-methylbenzyl alcohol 
• 534-22-5 2-methylfuran 
• 6345-56-8 1-methyl-7-oxa-bicyclo[2.2.1]heptane-2endo,3endo-dicarboxylic acid anhydride 
• 130403-08-6 D₂₉₁₆ 
• 67-56-1 methanol 
• 14920-81-1 methyl 2,6-dimethylbenzoate 

Downstream Products

• 63113-01-9 7-Methylphthalaldehydsaeure 
• 63112-99-2 2-Formyl-6-methylbenzoesaeuremethylester 
• 20771-96-4 2-carboxy-3-methylbenzaldehyde 
• 90534-48-8 2-(hydroxymethyl)-3-methylbenzyl alcohol 

Relevant articles and documents

Dehydrogenative lactonization of diols in aqueous media catalyzed by a water-soluble iridium complex bearing a functional bipyridine ligand

A new catalytic system for the dehydrogenative lactonization of a variety of benzylic and aliphatic diols in aqueous media was developed. By using a water-soluble, dicationic iridium catalyst bearing 6,6′-dihydroxy-2, 2′-bipyridine as a functional ligand, highly atom economical and environmentally benign synthesis of various lactones was achieved in good to excellent yields. Recovery and reuse of the catalyst were also accomplished by a simple phase separation and the recovered catalyst maintained its high activity at least until the fifth run. Copyright

Chemical oxidation of an anticonvulsant N-(5'-methylisoxazol-3-yl) 2,6- dimethylbenzamide (D2916)

The new anticonvulsant N-(5'-methylisoxazol-3-yl)-2,6-dimethylbeazamide (D2916), which presents two kinds of methyl groups which could be oxidized, was submitted to various chemical oxidizing agents. Several sites and degrees of oxidation were observed. The main oxidized site was the arylmethyl group without cleavage of the isoxazole ring, leading via carboxylic acid and primary alcohol intermediates to phthalimide and lactame derivatives. In no case was the methyl group of the isoxazole moiety hydroxylated.

OXIDATION OF SUBSTITUTED 2-METHYL BENZOIC ACIDS AND ACRYLIC ACIDS BY S2O8(2-)-Ag(I); THEIR CONVERSION TO PHTHALIDES AND BUTENOLIDES THROUGH REARRANGEMENT OF ACYLOXYL RADICALS.

Ag (I) mediated persulphate oxidation of various 2-methyl benzoic acids and acrylic acids, co-catalysed by Cu (II), leads to unsaturated γ-lactones, together with decarboxylation products.Lactonisation proceeds through 1,5 hydrogen trasfer from intermediate acyloxyl radicals.