63500-40-3 Usage
Description
1-(2,3,5-tri-O-acetylpentofuranosyl)pyrimidin-2(1H)-one, also known as 2',3',5'-tri-O-acetyluridine, is a nucleoside derivative that features a pyrimidine base connected to a ribose sugar molecule. 1-(2,3,5-tri-O-acetylpentofuranosyl)pyrimidin-2(1H)-one is widely utilized in biochemistry and molecular biology research as a precursor for the synthesis of modified nucleosides and nucleotides. The presence of acetyl groups on the ribose sugar offers protection to the hydroxyl groups, facilitating easier manipulation and modification of the molecule in various chemical reactions. Owing to its modified structure, 2',3',5'-tri-O-acetyluridine holds potential applications in the development of nucleoside analogs for therapeutic use in antiviral and anticancer treatments. Furthermore, it serves as a substrate for enzymes involved in nucleotide metabolism studies.
Uses
Used in Biochemistry and Molecular Biology Research:
1-(2,3,5-tri-O-acetylpentofuranosyl)pyrimidin-2(1H)-one is used as a precursor for the synthesis of modified nucleosides and nucleotides, allowing researchers to explore novel chemical modifications and potential applications in various fields.
Used in Antiviral and Anticancer Treatments:
In the pharmaceutical industry, 1-(2,3,5-tri-O-acetylpentofuranosyl)pyrimidin-2(1H)-one is used as a starting material for the development of nucleoside analogs, which have potential therapeutic applications in antiviral and anticancer treatments. These analogs can be designed to target specific viral or cancer-related processes, offering new treatment options for patients.
Used in Enzyme Studies:
1-(2,3,5-tri-O-acetylpentofuranosyl)pyrimidin-2(1H)-one is used as a substrate for enzymes involved in nucleotide metabolism studies. This application aids researchers in understanding the mechanisms of enzyme action and the role of nucleotides in cellular processes, which can contribute to the development of targeted therapies for various diseases.
Overall, 1-(2,3,5-tri-O-acetylpentofuranosyl)pyrimidin-2(1H)-one is a versatile compound with significant potential in various scientific and medical applications, making it a valuable asset in the fields of biochemistry, molecular biology, and pharmaceutical research.
Check Digit Verification of cas no
The CAS Registry Mumber 63500-40-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,5,0 and 0 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 63500-40:
(7*6)+(6*3)+(5*5)+(4*0)+(3*0)+(2*4)+(1*0)=93
93 % 10 = 3
So 63500-40-3 is a valid CAS Registry Number.
63500-40-3Relevant articles and documents
Evaluation of α-pyrones and pyrimidones as photoaffinity probes for affinity-based protein profiling
Battenberg, Oliver A.,Nodwell, Matthew B.,Sieber, Stephan A.
experimental part, p. 6075 - 6087 (2011/10/09)
α-Pyrones and pyrimidones are common structural motifs in natural products and bioactive compounds. They also display photochemistry that generates high-energy intermediates that may be capable of protein reactivity. A library of pyrones and pyrimidones was synthesized, and their potential to act as photoaffinity probes for nondirected affinity-based protein profiling in several crude cell lysates was evaluated. Further "proof-of-principle" experiments demonstrate that a pyrimidone tag on an appropriate scaffold is equally capable of proteome labeling as a benzophenone.
