638217-08-0

Basic information

• Product Name: 6-Hydroxy-N,2-dimethylbenzofuran-3-carboxamide
• Synonyms: 6-Hydroxy-N-methyl-2-methyl-1-benzofuran-3-carboxamide;6-Hydroxy-N,2-dimethylbenzofuran-3-carboxamide;EOS-61056;6-hydroxy-N,2-dimethyl-1-benzofuran-3-carboxamide;6-HYDROXY-N,2-DIMETHYLBENZOFURAN-3-CARBOXAMIDE(WXG01735)
• CAS NO: 638217-08-0
• Molecular Formula: C₁₁H₁₁NO₃
• Molecular Weight: 205.21
• Mol File: 638217-08-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 259.1 °C at 760 mmHg
• Flash Point: 110.5 °C
• Appearance: /
• Density: 1.271
• Vapor Pressure: 0.00819mmHg at 25°C
• Refractive Index: 1.62
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 6-Hydroxy-N,2-dimethylbenzofuran-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Hydroxy-N,2-dimethylbenzofuran-3-carboxamide(638217-08-0)
• EPA Substance Registry System: 6-Hydroxy-N,2-dimethylbenzofuran-3-carboxamide(638217-08-0)

Safety Data

• Hazardous Substances Data: 638217-08-0(Hazardous Substances Data)

Usage

General Description

6-Hydroxy-N,2-dimethylbenzofuran-3-carboxamide is a chemical compound with the molecular formula C12H13NO3. It is a benzofuran derivative that contains a carboxamide group and a hydroxy group. 6-Hydroxy-N,2-dimethylbenzofuran-3-carboxamide is commonly used as a building block in organic synthesis and medicinal chemistry. It has been studied for its potential pharmaceutical applications, particularly in the development of new drugs for various therapeutic purposes. Its chemical structure and properties make it a valuable tool in the development of novel compounds with potential pharmacological activities.

InChI:InChI=1/C11H11NO3/c1-6-10(11(14)12-2)8-4-3-7(13)5-9(8)15-6/h3-5,13H,1-2H3,(H,12,14)

Upstream product

• 638217-07-9 6-methoxy-2-methylbenzofuran-3-carboxylic acid methylamide 
• 854515-52-9 6-hydroxy-2-methyl-benzofuran-3-carboxylic acid 
• 74-89-5 methylamine 
• 593-51-1 methylamine hydrochloride 
• 150-19-6 O-methylresorcine 
• 63604-94-4 2-bromo-5-methoxyphenol 
• 328945-89-7 2-Acetoxy-1-bromo-4-methoxybenzene 

Downstream Products

• 1194506-26-7 6-(6,7-dimethoxyquinazolin-4-yloxy)-N,2-dimethylbenzofuran-3-carboxamide 
• 854514-88-8 N,2-dimethyl-6-[7-(2-morpholinoethoxy)quinolin-4-yloxy]benzofuran-3-carboxamide 

Relevant articles and documents

Synthetic method of VEGFR inhibitor furoquitinib and benzofuran intermediate thereof

The invention discloses a synthetic method of a VEGFR inhibitor furoquitinib and a benzofuran intermediate thereof. The synthetic method of the VEGFR inhibitor furoquitinib comprises the following steps of S1, halogenation, S2, acylation, S3, coupling, S4

NOVEL QUINOLINE DERIVATIVES

The invention relates to compounds represented by Formula (I): and to pharmaceutically acceptable salts or solvates of said compounds, wherein each of A, R3-8, X3, X5, m, and n are defined herein. The invention also relates to pharmaceutical compositions containing the compounds of Formula (I) and to methods of treating hyperproliferative disorders in a mammal by administering compounds of Formula (I).

BENZOFUSED HETEROARYL AMIDE DERIVATIVES OF THIENOPYRIDINES USEFUL AS THERAPEUTIC AGENTS, PHARMACEUTICAL COMPOSITIONS INCLUDING THE SAME, AND METHODS FOR THEIR USE

The invention relates to compounds represented by the formula I and to prodrugs or metabolites thereof, or pharmaceutically acceptable salts or solvates of said compounds, said prodrugs, and said metabolites, wherein Z, Y, R11 and R14, R15, R16, and R17 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula I and to methods of treating hyperproliferative disorders in a mammal by administering the compounds of formula I.