6414-28-4

Basic information

• Product Name: N-(2,4-dibromo-6-methylphenyl)-4-methylbenzamide
• CAS NO: 6414-28-4
• Molecular Formula: C₁₅H₁₃Br₂NO
• Molecular Weight: 383.0778
• Mol File: 6414-28-4.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 368.6°C at 760 mmHg
• Flash Point: 176.7°C
• Density: 1.642g/cm³
• Vapor Pressure: 1.26E-05mmHg at 25°C
• Refractive Index: 1.657
• CAS DataBase Reference: N-(2,4-dibromo-6-methylphenyl)-4-methylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2,4-dibromo-6-methylphenyl)-4-methylbenzamide(6414-28-4)
• EPA Substance Registry System: N-(2,4-dibromo-6-methylphenyl)-4-methylbenzamide(6414-28-4)

Safety Data

• Hazardous Substances Data: 6414-28-4(Hazardous Substances Data)

Upstream product

• 19098-31-8 3,4-epoxy-1-butanol 
• 124-38-9 carbon dioxide 
• 3068-00-6 D,L-1,2,4-butanetriol 
• 57-13-6 urea 
• 616-38-6 carbonic acid dimethyl ester 
• 102-09-0 bis(phenyl) carbonate 
• 201230-82-2 carbon monoxide 
• 171110-94-4 4-<(2-benzyloxy)ethyl>-1,3-dioxolan-2-one 
• 42890-76-6 (S)-1,2,4-butanetriol 
• 530-62-1 1,1'-carbonyldiimidazole 
• 32315-10-9 bis(trichloromethyl) carbonate 

Relevant articles and documents

Substrate-Controlled Product Divergence: Conversion of CO2 into Heterocyclic Products

Substituted epoxy alcohols and amines allow substrate-controlled conversion of CO2 into a wide range of heterocyclic structures through different mechanistic manifolds. This new approach results in an unusual scope of CO2-derived products by initial activation of CO2 through either the amine or alcohol unit, thus providing nucleophiles for intramolecular epoxy ring opening under mild reaction conditions. Control experiments support the crucial role of the amine/alcohol fragment in this process with the nucleophile-assisted ring-opening step following an SNi pathway, and a 5-exo-tet cyclization, thus leading to heterocyclic scaffolds.

SYNTHESIS OF CYCLIC CARBONATES

The present invention provides a method of synthesizing a cyclic carbonate comprising the step of reacting an alcohol with carbon dioxide.in the presence of a base.

Monomers containing 2′-O-alkoxymethyl groups as synthons for the oligonucleotide synthesis by the phosphotriester method

A general scheme for the synthesis of ribonucleotides containing an alkoxymethyl group at the 2′-O-position of ribose and an O-nucleophilic catalytic 4-methoxy-1-oxido-2-picolyl phosphate-protecting group has been developed for the introduction into oligonucleotides during their solid-phase synthesis by the phosphotriester method. The scheme has been tested in the synthesis of monomers with 2′-O-modifying groups as examples: 2-azidoethoxymethyl, propargyloxymethyl, and 3,4-cyclocarbonatebutoxymethyl groups.