643-77-6

Basic information

• Product Name: Benzeneacetic acid, a-fluoro-, ethyl ester
• CAS NO: 643-77-6
• Molecular Formula: C10H11FO2
• Molecular Weight: 182.195
• Mol File: 643-77-6.mol
• Article Data: 40

Chemical Properties

• CAS DataBase Reference: Benzeneacetic acid, a-fluoro-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetic acid, a-fluoro-, ethyl ester(643-77-6)
• EPA Substance Registry System: Benzeneacetic acid, a-fluoro-, ethyl ester(643-77-6)

Safety Data

• Hazardous Substances Data: 643-77-6(Hazardous Substances Data)

Upstream product

• 2882-19-1 ethyl 2-phenyl-2-bromoacetate 
• 64-17-5 ethanol 
• 1578-63-8 d'acide 2-fluoro-2-phenyl acetique 
• 774-40-3 hydroxy-phenyl-acetic acid ethyl ester 
• 1117-96-0 Diazoethan 
• 101-97-3 Ethyl 2-phenylethanoate 
• 83-13-6 diethyl 2-phenylmalonate 
• 401-55-8 ethyl bromofluoroacetate 
• 98-80-6 phenylboronic acid 
• 3389-53-5 phenylacetylpyrrolidine 
• 108-86-1 bromobenzene 
• 401-56-9 ethyl chlorofluoroacetate 
• 3262-89-3 triphenylboroxine 
• 100701-49-3 3-ethoxy-2-fluoro-3-oxopropionic acid 

Downstream Products

• 247039-05-0 (R_S)-(+)-2-[N-(p-toluenesulfinamido)]-3-(S)-fluoro-3-phenylpropionitrile 
• 247039-08-3 (R_S)-(-)-2-[N-(p-toluenesulfinamido)]-3-(R)-fluoro-3-phenylpropionitrile 
• 13344-76-8 α-fluorobenzeneacetaldehyde 
• 2802-98-4 diethyl 2-fluoro-2-phenylmalonate 
• 1578-63-8 d'acide 2-fluoro-2-phenyl acetique 
• 3468-99-3 ethyl diphenylacetate 
• 21120-43-4 1-phenyl-1-fluoro-2-propanone 
• 29114-82-7 1-Fluoro-1-phenyl-hexan-2-one 
• 32154-48-6 4-Fluoro-2,2-dimethyl-3-oxo-4-phenyl-butyric acid ethyl ester 
• 21120-42-3 6-phenyl-decan-5-one 
• 1126-71-2 N,N-dimethylphenethylamine 
• 14204-06-9 α-fluoro-N,N-dimethylbenzeneacetamide 
• 14204-07-0 2-fluoro-2-phenylacetamide 

Relevant articles and documents

Nickel-Catalyzed Cross-Coupling of Ethyl Chlorofluoroacetate with Aryl Bromides

A combinatorial nickel-catalyzed monofluoroalkylation of aryl bromides with the industrial raw regent ethyl chlorofluoroacetate has been developed. The two key factors to successful conversion are the combination of nickel with readily available nitrogen and phosphine ligands and the using of a mixture of different solvents. Mechanistic investigations indicated a new zinc regent might generated in situ and be involved in the reaction process.

Divergent Synthesis of α-Fluorinated Carbonyl and Carboxyl Derivatives by Double Electrophilic Activation of Amides

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