643746-88-7

Basic information

• Product Name: 5-(2-methoxyphenyl)pentanoic acid ethyl ester
• Synonyms: 5-(2-methoxyphenyl)pentanoic acid ethyl ester
• CAS NO: 643746-88-7
• Molecular Weight: 236.311
• Mol File: 643746-88-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 5-(2-methoxyphenyl)pentanoic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2-methoxyphenyl)pentanoic acid ethyl ester(643746-88-7)
• EPA Substance Registry System: 5-(2-methoxyphenyl)pentanoic acid ethyl ester(643746-88-7)

Safety Data

• Hazardous Substances Data: 643746-88-7(Hazardous Substances Data)

Upstream product

• 55001-09-7 methyl 3-(2-methoxyphenyl)propanoate 
• 6342-77-4 2-methoxy-benzenepropanoic acid 
• 1011-54-7 2-methoxycinnamic acid 
• 70311-27-2 2-methoxybenzenepropanoic acid ethyl ester 
• 33877-05-3 ethyl 3-(2-methoxyphenyl)acrylate 
• 33538-83-9 3-(2-methoxyphenyl)propanal 
• 135-02-4 ortho-anisaldehyde 
• 10493-37-5 3-(2-methoxyphenyl)propan-1-ol 
• 612-16-8 (2-methoxyphenyl)methanol 
• 42516-28-9 ethyl (2E)-4-(diethoxyphosphoryl)crotonate 
• 1019654-18-2 (2E,4E)-ethyl 5-(2-methoxyphenyl)penta-2,4-dienoate 
• 408308-34-9 ethyl 5-(2-methoxyphenyl)pentadienoate 
• 110949-94-5 1-ethoxycarbonyl-4-(2-methoxyphenyl)but-3-ene 

Downstream Products

• 408308-07-6 5-(2'-methoxyxyphenyl)pentanoic acid 
• 1452406-11-9 1,1,1-trifluoro-6-(2-methoxyphenyl)hexan-2-one 
• 1452406-20-0 1,1,1,2,2-pentafluoro-7-(2-methoxyphenyl)heptan-3-one 
• 14374-55-1 5-(2-methoxyphenyl)pentan-1-ol 

Relevant articles and documents

Synthesis, in vitro and in silico evaluation of diaryl heptanones as potential 5LOX enzyme inhibitors

A new series of diaryl heptanones (12a-q) were synthesized and their structures were confirmed by its 1H, 13C NMR and Mass spectral data. These analogs were evaluated for their anti-oxidant activity and potential to inhibit 5-lipoxygenase. Compounds 12k and 12o showed potent in vitro 5-lipoxygenase enzyme inhibitory activity with IC50 values of 22.2, 21.5 μM, which are comparable to curcumin (24.4 μM). Further they also have shown significant antioxidant activity. Molecular docking studies clearly showed correlation between binding energy and potency of these compounds.

Discovery of synthetic methoxy-substituted 4-phenylbutyric acid derivatives as chemical chaperones

In this study, we evaluated the chemical chaperone activity of synthetic 4-phenylbutyric acid (4-PBA) derivatives. These derivatives have a methoxy group at the benzene ring and/or longer or shorter fatty acid portions. Several 4-PBA derivatives demonstrated higher antiaggregation activity than 4-PBA. Moreover, 4-(4-methoxyphenyl)butanoic acid (7b) showed protective effects against endoplasmic reticulum stress-induced neuronal cell death.

SECONDARY AMINO ANILINIC PIPERIDINES AS MCH1 ANTAGONISTS AND USES THEREOF

This invention is directed to compounds which are selective antagonists for melanin concentrating hormone-1 (MCH1) receptors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier. This invention provides a pharmaceutical composition made by combining a therapeutically effective amount of the compound of this invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of the compounds of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of reducing the body mass of a subject which comprises administering to the subject an amount of a compound of the invention effective to reduce the body mass of the subject. This invention further provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the invention effective to treat the subject=s depression and/or anxiety. This invention further provides a method of treating a subject suffering from a urinary disorder.