645-12-5 Usage
Description
5-Nitro-2-furoic acid is a yellow crystalline powder and a representative of 2-substituted 5-nitrofurans, which are a class of compounds with various applications in the pharmaceutical, veterinary, and agricultural industries.
Uses
Used in Pharmaceutical and Veterinary Medicine:
5-Nitro-2-furoic acid is used as an active pharmaceutical ingredient for its antibacterial, antiprotozoal, and anthelmintic properties. It is utilized in human and veterinary medicines to treat various infections and diseases.
Used in Food Preservation and Feed Additives:
5-Nitro-2-furoic acid is used as a preservative in the food industry and as an additive in the animal feed industry to maintain the quality and safety of the products.
Used in Research and Development:
5-Nitro-2-furoic acid is used as a chemical intermediate in the preparation of [1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles, which are compounds of interest in the field of chemistry and material science.
Used in Chemical Property Analysis:
The FT-IR and FT-Raman spectra of 5-Nitro-2-furoic acid have been studied, providing valuable information about its chemical properties and potential applications in various industries.
Environmental Fate
5-Nitro-2-furoic acid is a yellow crystalline powder with molecular
weight of 157.08 g mol-1 and density of 1.72 g cm-3. The
boiling point is 332.4 ℃ and the melting point is 185.00–
189.00 ℃ at 760 mm Hg. Vapor pressure is 5.83E-05 mm Hg
at 25 ℃ and enthalpy of vaporization is 60.71 kJ mol-1.
5-Nitro-2-furoic acid is very soluble in water. It is stable under
normal temperature and pressure.
Toxicity evaluation
The toxicological properties of this compound have not been
fully investigated. However, as a minimum precaution, it
should be considered harmful. Precautions should be taken
and procedures adopted to prevent exposure.
Check Digit Verification of cas no
The CAS Registry Mumber 645-12-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,4 and 5 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 645-12:
(5*6)+(4*4)+(3*5)+(2*1)+(1*2)=65
65 % 10 = 5
So 645-12-5 is a valid CAS Registry Number.
InChI:InChI=1/C5H3NO5/c7-5(8)3-1-2-4(11-3)6(9)10/h1-2H,(H,7,8)/p-1
645-12-5Relevant articles and documents
-
Krapivin et al.
, (1975)
-
Hydroperoxide oxidation of different organic compounds catalyzed by silica-supported selenenamide
Giurg,Brzaszcz,Mlochowski
, p. 417 - 428 (2007/10/03)
The recoverable heterogeneous silica-supported catalyst selenenamide 2 was prepared by the coupling of 3-aminopropylsilicate (4) with 2-chloroselenobenzoyl chloride (6). Its catalytic activity was demonstrated in tert-butyl hydroperoxide oxidation of aldehydes 8 to carboxylic acids 9 and benzylamines 17 to nitriles 18. Moreover, it was employed for hydrogen peroxide oxidation of azomethine compounds such as tosylhydrazones 10, oximes 13 and N,N-dimethylhydrazones 16 to parent ketones 12, arenecarboxylic acids 11 and 15, their methyl esters 14 and nitriles 18 depending on the substrate used and the reaction conditions. The catalyst was simply recovered by filtration and could be reused.
Method for stimulating hair growth with cationic derivative of minoxidil using therapeutic iontophoresis
-
, (2008/06/13)
This invention relates to a method of applying a cationic derivative of Minoxidil which is transported by means of iontophoresis to hair follicles where the cationic derivatives promote hair growth. Each of the cationic derivatives of Minoxidil are synthesized by reacting the Minoxidil parent compound with an organic or an inorganic acid to form the cationic derivative.
