6450-57-3

Basic information

• Product Name: 1-(2-MESITYLENE)-1,3-BUTANEDIONE
• Synonyms: (2,4,6-TRIMETHYLBENZOYL)ACETONE;1-(2,4,6-TRIMETHYLBENZENE)-1,3-BUTANEDIONE;1-(2-MESITYLENE)-1,3-BUTANEDIONE;Mesitylenebutanedione;1-(2-MESITYLENE)-1,3-BUTANEDIONE 96+%;1-(2,4,6-Trimethylbenzene)-1,3-butanedione (2,4,6-Trimethylbenzoyl)acetone;1-Mesitylbutane-1,3-dione;1-(2,4,6-Trimethylphenyl)-1,3-butanedione
• CAS NO: 6450-57-3
• Molecular Formula: C₁₃H₁₆O₂
• Molecular Weight: 204.26
• Mol File: 6450-57-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 45°C
• Boiling Point: 172 °C / 22mmHg
• Flash Point: 119.8 °C
• Appearance: /
• Density: 1.021 g/cm³
• Solubility: within almost transparency in Methanol
• CAS DataBase Reference: 1-(2-MESITYLENE)-1,3-BUTANEDIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-MESITYLENE)-1,3-BUTANEDIONE(6450-57-3)
• EPA Substance Registry System: 1-(2-MESITYLENE)-1,3-BUTANEDIONE(6450-57-3)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 6450-57-3(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 75, p. 4109, 1953 DOI: 10.1021/ja01112a534

Upstream product

• 108-24-7 acetic anhydride 
• 108-67-8 1,3,5-trimethyl-benzene 
• 1667-01-2 2,4,6-Trimethylacetophenone 
• 925-90-6 ethylmagnesium bromide 

Downstream Products

• 58529-96-7 γ-bromoacetoacetylmesitylene 
• 42797-59-1 Acetyl-(2,4,6-trimethylbenzoyl)-diazomethan 
• 103212-29-9 2,5-Dimethyl-3,4-bis-(2,4,6-trimethyl-benzoyl)-furan 
• 107504-91-6 2-(5,6-Dihydro-imidazo[2,1-b]thiazol-3-yl)-1-(2,4,6-trimethyl-phenyl)-ethanol; hydrochloride 
• 107504-57-4 2-(5,6-Dihydro-imidazo[2,1-b]thiazol-3-yl)-1-(2,4,6-trimethyl-phenyl)-ethanone; hydrobromide 
• 107504-72-3 2-[5,6-Dihydro-imidazo[2,1-b]thiazol-(3E)-ylidene]-1-(2,4,6-trimethyl-phenyl)-ethanone 
• 828283-35-8 3-mesityl-5-methyl-N-phenylpyrazole 
• 681478-34-2 5-methyl-3-(2,4,6-trimethylphenyl)-1H-pyrazole 
• 7642-32-2 2-butadiynyl-1,3,5-trimethyl-benzene 
• 1175012-28-8 1-(2,4,6-trimethyl-phenyl)-butane-1,2,3-trione-2-oxime 
• 39755-80-1 1-Triaethylsilyl-6-mesityl-hexa-1,3,5-triin 
• 39231-43-1 1,12-Bismesityldodecahexain 
• 39231-52-2 1,12-Bismesityldodecan 

Relevant articles and documents

An improved synthesis of 2-diazo-1,3-diketones

The sodium hydride/dibenzo-18-crown-6 ether system was found to be an effective base for the synthesis of 1,3-diketones by the Claisen condensation. The use of potassium fluoride (with or without crown ether) as the base in diazo-transfer reactions extends this reaction to the synthesis of hindered diazo diketones. In the case of isomeric 1,3-diketones, the stereoselectivity of the process considerably rises.

Process for the manufacture of aromatic 1,3-diketones

Aromatic 1,3-diketones are produced by reacting aromatic compounds with acetoacetyl fluoride optionally substituted in γ-position by fluorine, chlorine and/or bromine, in hydrofluoric acid of at least 90% strength at a temperature of from about -40 to +50°C. The products obtained are important starting products and intermediates for the manufacture of dyestuffs, plastics and pharmaceuticals. Furthermore they can be used for the formation of metal complexes and metal extracting agents, solution intermediaries and solvents.