64750-89-6Relevant articles and documents
Synthesis of new β-trifluoromethyl containing GABA and β-fluoromethyl containing N-benzylpyrrolidinones
Gerus, Igor I.,Mironets, Roman V.,Shaitanova, Elena N.,Kukhar, Valery P.
scheme or table, p. 224 - 228 (2010/04/30)
A whole series of 3-(mono-, di-, trifluoro)methyl-substituted N-benzylpyrrolidinones 5a-c was synthesized by deoxyfluorination of corresponding 3-functionalized N-benzylpyrrolidinones. New β-trifluoromethyl containing GABA 4a was obtained in two alternative ways: by successive hydrolysis and hydrogenolysis of 3-trifluoromethyl N-benzylpyrrolidinone 5a and from trifluoroacetone as starting compound.
Antiinflammatory activity of a series of substituted 2,3-dihydro-6-hydroxypyrimido[2,1-f]purine-4,8(1H,9H)-diones
Kaminski,Solomon,Conn,Wong,Chiu,Massa,Siegel,Watnick
, p. 1118 - 1127 (2007/10/02)
A series of substituted analogues based on the novel 2,3-dihydro-6-hydroxypyrimido[2,1-f]purine-4,8(1H,9H)-dione ring system have been synthesized and shown to exhibit antiinflammatory activity in the adjuvant-induced arthritis rat model (AAR). The activi
Synthesis and Thermolysis of Highly Halogenated Δ1-Pyrazolines
Huff, Roger K.,Savins, Eric G.
, p. 742 - 743 (2007/10/02)
The pyrolysis of highly halogenated Δ1-pyrazolines gives, in addition to cyclopropanes, rearranged olefins.
