64890-49-9

Basic information

• Product Name: Azirino[2,1-a]isoquinoline-1-carboxylic acid, 1,3,4,8b-tetrahydro-, ethyl ester, cis-
• CAS NO: 64890-49-9
• Molecular Formula: C13H15NO2
• Mol File: 64890-49-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Azirino[2,1-a]isoquinoline-1-carboxylic acid, 1,3,4,8b-tetrahydro-, ethyl ester, cis-(CAS DataBase Reference)
• NIST Chemistry Reference: Azirino[2,1-a]isoquinoline-1-carboxylic acid, 1,3,4,8b-tetrahydro-, ethyl ester, cis-(64890-49-9)
• EPA Substance Registry System: Azirino[2,1-a]isoquinoline-1-carboxylic acid, 1,3,4,8b-tetrahydro-, ethyl ester, cis-(64890-49-9)

Safety Data

• Hazardous Substances Data: 64890-49-9(Hazardous Substances Data)

Upstream product

• 24423-87-8 3,4-dihydro-isoquinoline 2-oxide 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 

Relevant articles and documents

Nitrones. 6. Reactions of Nitrones with Cyclic Phosphonates. Influence of the Phosphonate Ring Size upon the Course of the Reaction

Nitrones, 5,5-dimethyl-Δ1-pyrroline N-oxide (5), and 3,4-dihydroisoquinoline N-oxide (6) were reacted with the five-membered cyclic phosphonates 2--2-oxo-4,5-dimethyl-1,3,2-dioxaphospholane (1) and 2-(cyanomethyl)-2-oxo-4,5-dimethyl-1,3,2-dioxaphospholane (2) and with the six-membered cyclic phosphonates 2--2-oxo-5,5-dimethyl-1,3,2-dioxaphosphorinane (3) and 2-(cyanomethyl)-2-oxo-5,5-dimethyl-1,3,2-dioxaphosphorinane (4).The reactions of the five-membered phosphonates gave aziridines as products, except that of 6 and 2.The reactions of the six-membered phosphonates gave exclusively or predominantly enamines.The reactions of C-phenyl-N-methylnitrone (7) with 2 gave only trans-1-methyl-2-cyano-3-phenylaziridine (22).Cyclic phosphates 2-hydroxy-2-oxo-4,5-dimethyl-1,3,2-dioxaphospholane (20) and 2-hydroxy-2-oxo-5,5-dimethyl-1,3,2-dioxaphosphorinane (21) were isolated as byproducts from the reactions of the corresponding phosphonates.