65420-47-5Relevant articles and documents
Access to Enantioenriched Organosilanes from Enals and β-Silyl Enones: Carbene Organocatalysis
Zhang, Yuxia,Huang, Jie,Guo, Yingying,Li, Lin,Fu, Zhenqian,Huang, Wei
, p. 4594 - 4598 (2018/03/21)
Herein, an efficient route to enantioenriched organosilanes, containing two consecutive stereogenic centers, from enals and β-silyl enones under carbene organocatalysis is described. Under mild reaction conditions, this transition-metal-free strategy exhibits a broad substrate scope, and excellent diastereo- and enantioselectivity.
Novel sequential 1,4-Brook rearrangement-Wittig reaction: New one-pot approach for silyl dienol ethers
Matsuya, Yuji,Koiwai, Azusa,Minato, Daishiro,Sugimoto, Kenji,Toyooka, Naoki
, p. 5955 - 5957,3 (2020/07/31)
A novel one-pot synthetic method of silyl dienol ethers via 1,4-Brook rearrangement-Wittig reaction sequence has been developed. This tandem reaction proceeded via the intramolecular silyl migration step, which enabled stereoselective formation of phosphorane intermediates. The reaction is operationally simple and high yielding, thus providing a new useful formula for silyl dienol ether synthesis.
Cu-catalyzed asymmetric conjugate additions of dialkyl- and diarylzinc reagents to acyclic β-silyl-α,β-unsaturated ketones. Synthesis of allylsilanes in high diastereo- and enantiomeric purity
Kacprzynski, Monica A.,Kazane, Stephanie A.,May, Tricia L.,Hoveyda, Amir H.
, p. 3187 - 3190 (2008/02/11)
A readily available and simple (MW = 444.5 g/mol) valine-based chiral phosphine is used to promote highly efficient catalytic asymmetric conjugate additions of dialkyl- and diarylzinc reagents to acyclic β-silyl-α, β-unsaturated ketones. The catalytic asy
