65662-88-6

Basic information

• Product Name: 4-BROMO DIPHENYL SULFIDE
• Synonyms: 4-BROMO DIPHENYL SULFIDE;4-Bromodiphenylsulphide;1-Bromo-4-phenylsulfanylbenzene;4-Bromo diphenyl sul
• CAS NO: 65662-88-6
• Molecular Formula: C₁₂H₉BrS
• Molecular Weight: 265.17
• Mol File: 65662-88-6.mol
• Article Data: 98

Chemical Properties

• Boiling Point: 355.6 °C at 760 mmHg
• Flash Point: 168.8 °C
• Appearance: /
• Density: 1.49 g/cm³
• Vapor Pressure: 6.35E-05mmHg at 25°C
• Refractive Index: 1.681
• CAS DataBase Reference: 4-BROMO DIPHENYL SULFIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO DIPHENYL SULFIDE(65662-88-6)
• EPA Substance Registry System: 4-BROMO DIPHENYL SULFIDE(65662-88-6)

Safety Data

• Hazardous Substances Data: 65662-88-6(Hazardous Substances Data)

Usage

General Description

4-Bromo diphenyl sulfide is a chemical compound with the molecular formula C12H9BrS. It is a crystalline solid with a pale yellow color, and it is commonly used in organic synthesis and as a building block for various chemical reactions. 4-BROMO DIPHENYL SULFIDE is known for its strong odor and is considered to be hazardous if it comes into contact with the skin or if it is ingested. It is also used in the production of pharmaceuticals, dyes, and agricultural chemicals. 4-Bromo diphenyl sulfide is also known to be an effective flame retardant in some applications. Overall, it is an important industrial chemical with various uses in different industries.

InChI:InChI=1/C12H9BrS/c13-10-6-8-12(9-7-10)14-11-4-2-1-3-5-11/h1-9H

Upstream product

• 106-37-6 1.4-dibromobenzene 
• 108-98-5 thiophenol 
• 945-51-7 1,1'-sulfinylbisbenzene 
• 10035-10-6 hydrogen bromide 
• 64-19-7 acetic acid 
• 56-23-5 tetrachloromethane 
• 139-66-2 diphenyl sulfide 
• 110-54-3 hexane 
• 5335-84-2 bis(4-bromophenyl)disulfide 
• 98-80-6 phenylboronic acid 
• 591-50-4 iodobenzene 
• 106-53-6 para-bromobenzenethiol 
• 71-43-2 benzene 
• 2996-92-1 phenyl trimethylsiloxane 

Downstream Products

• 108-86-1 bromobenzene 
• 106-37-6 1.4-dibromobenzene 
• 3393-78-0 4,4'-dibromodiphenyl sulfide 
• 88519-49-7 (4-iodophenyl)(phenyl)thioether 
• 96802-31-2 1-phenylsulfanyl-4-p-tolylsulfanyl-benzene 
• 60420-81-7 (4-chlorophenyl)(4-(phenylthio)phenyl)sulfane 
• 1262235-31-3 1-phenylsulfanyl-4-o-tolylsulfanyl-benzene 
• 23038-36-0 1-bromo-4-(phenylsulphonyl)benzene 
• 25186-92-9 1-bromo-4-(phenylsulfinyl)benzene 
• 52872-99-8 4-phenylmercaptothiophenol 
• 61654-48-6 N-phenyl-4-(phenylsulfonyl)benzenamine 
• 97442-87-0 1-ethynyl-4-(phenylsulfonyl)benzene 

Relevant articles and documents

Ni(II) Precatalysts Enable Thioetherification of (Hetero)Aryl Halides and Tosylates and Tandem C?S/C?N Couplings

Ni-catalyzed C?S cross-coupling reactions have received less attention compared with other C-heteroatom couplings. Most reported examples comprise the thioetherification of most reactive aryl iodides with aromatic thiols. The use of C?O electrophiles in this context is almost uncharted. Here, we describe that preformed Ni(II) precatalysts of the type NiCl(allyl)(PMe2Ar’) (Ar’=terphenyl group) efficiently couple a wide range of (hetero)aryl halides, including challenging aryl chlorides, with a variety of aromatic and aliphatic thiols. Aryl and alkenyl tosylates are also well tolerated, demonstrating, for the first time, to be competent electrophilic partners in Ni-catalyzed C?S bond formation. The chemoselective functionalization of the C?I bond in the presence of a C?Cl bond allows for designing site-selective tandem C?S/C?N couplings. The formation of the two C-heteroatom bonds takes place in a single operation and represents a rare example of dual electrophile/nucleophile chemoselective process.

Chan-Lam-Type C-S Coupling Reaction by Sodium Aryl Sulfinates and Organoboron Compounds

A Chan-Lam-Type C-S coupling reaction using sodium aryl sulfinates has been developed to provide diaryl thioethers in up to 92% yields in the presence of a copper catalyst and potassium sulfite. Both electron-rich and electron-poor sodium aryl sulfinates and diverse organoboron compounds were tolerated for the synthesis of aryl and heteroaryl thioethers and dithioethers. The mechanistic study suggested that potassium sulfite was involved in the deoxygenation of sulfinate through a radical process.

N-bromosuccinimide/HCl mediated reduction of sulfoxides to sulfides

An efficient reduction of sulfoxides to sulfides mediated by N-bromosuccinimide (NBS)/HCl system has been developed. This protocol shows good functional group compatibility as well as broad substrates scope with operational simplicity.