65948-19-8

Basic information

• Product Name: 6-phenoxybenzo[d]thiazol-2-amine
• Synonyms: 6-phenoxybenzo[d]thiazol-2-amine;6-Phenoxy-1,3-benzothiazol-2-amine
• CAS NO: 65948-19-8
• Molecular Formula: C₁₃H₁₀N₂OS
• Molecular Weight: 242
• Mol File: 65948-19-8.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 6-phenoxybenzo[d]thiazol-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-phenoxybenzo[d]thiazol-2-amine(65948-19-8)
• EPA Substance Registry System: 6-phenoxybenzo[d]thiazol-2-amine(65948-19-8)

Safety Data

• Hazardous Substances Data: 65948-19-8(Hazardous Substances Data)

Usage

General Description

6-phenoxybenzo[d]thiazol-2-amine is a chemical compound with the molecular formula C14H10N2OS. It belongs to the benzo[d]thiazole class of compounds and contains a phenoxy group. This chemical has potential applications in the pharmaceutical industry, where it may be used as a building block in the synthesis of various bioactive molecules. Additionally, it may also have uses in the field of materials science, where it could be employed in the development of new organic materials with specific properties. Further research and experimentation are necessary to fully understand the potential uses and properties of 6-phenoxybenzo[d]thiazol-2-amine.

Upstream product

• 1135-14-4 4-aminophenyl phenyl sulfide 
• 31465-36-8 4-(4'-methoxyphenoxy)aniline 
• 333-20-0 potassium thioacyanate 
• 139-59-3 4-phenoxyanilin 
• 1147550-11-5 ammonium thiocyanate 
• 1747-60-0 6-methoxybenzothiazol-2-ylamine 
• 26278-79-5 2-amino-6-hydroxybenzothiazole 
• 108-90-7 chlorobenzene 
• 56705-84-1 4-(m-tolyloxy)aniline 
• 101-79-1 4-amino-4'-chlorodiphenyl ether 

Downstream Products

• 77736-57-3 2-amino-5-phenoxybenzenethiol 
• 129173-64-4 (2S,3S)-2,3-Dihydro-3-hydroxy-2-(4-methoxy-phenyl)-8-phenoxy-1,5-benzothiazepin-4(5H)-one 
• 129120-96-3 (2S,3S)-3-(2-amino-5-phenoxyphenyl)thio-2-hydroxy-3-(4-methoxyphenyl)propionic acid 
• 129120-52-1 (2S,3S)-5-(2-dimethylaminoethyl)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-8-phenoxy-1,5-benzothiazepin-4(5H)-one 
• 1163713-38-9 2-[3-(1,3-dioxo-1,3-dihydroisoindol-2-yl)propoxy]-N-(6-phenoxybenzothiazol-2-yl)benzamide 
• 1353280-30-4 N-butyl-6-phenoxybenzo[d]thiazol-2-amine 
• 1188043-84-6 C₁₃H₁₁N₃OS 

Relevant articles and documents

A Novel Difluoroacetic Acid Derivatives Compound, and Composition Comprising the Same

The present invention relates to a novel difluoroacetic acid derivative compound and a composition for various uses containing the same, wherein the difluoroacetic acid derivative compound can not only act as an agonist activating one among PPARandalpha;, andbeta; or andgamma;, but also can exhibit double efficacy or triple efficacy. Therefore, the difluoroacetic acid derivative compound can more effectively prevent, alleviate or treat metabolic diseases in which PPARs involves, and further exhibits whitening and wrinkle alleviation activity, and anti-inflammatory and antioxidant effects, thereby being able to be usefully utilized as various compositions.COPYRIGHT KIPO 2020

Copper-Catalyzed Aerobic Oxidative Regioselective Thiocyanation of Aromatics and Heteroaromatics

A copper-catalyzed aerobic oxidative reaction between aromatics or heteroaromatics with KSCN is developed by using O2 as the oxidant. The combination of Cu(OTf)2, N,N,N′,N′-tetramethylethylenediamine (TMEDA) and BF3·Et2O provides an efficient catalytic system, affording substituted thiocyanation products and 2-aminobenzothiazoles in excellent yields. The reaction also possesses a good functional group tolerance for both strong electron-withdrawing and electron-donating groups.

Synthesis and anticonvulsant activity evaluation of 7-alkoxy[1,2,4] triazolo[3,4-b]benzothiazol-3(2H)-ones

A new series of 7-alkoxy[1,2,4]triazolo[3,4-b]benzothiazol-3(2H)-ones were synthesized and evaluated for their anticonvulsant activities. Among these compounds, 7-propoxy[1,2,4]triazolo[3,4-b]benzothiazol-3(2H)-one (4c) and 7-butoxy[1,2,4]triazolo[3,4-b]benzothiazol-3(2H)-one (4d) showed the highest activity against maximal electroshock (MES)-induced tonic extension [effective dose (ED)50: 11.4 and 13.6 mg/kg, respectively]. It is worth mentioning that compound 4d showed especially low neurotoxicity, which led to a high protective index (PI >51). The orally anticonvulsant activity data of compound 4d further confirmed its efficacy, in an MES test, and its high safety with a PI value of 50.2. In addition, the potency of compound 4h against seizures induced by pentylenetetrazole, 3-mercaptopropionic acid, and bicuculline in the chemical-induced seizure tests suggested that compound 4d may exert its anticonvulsant activity through affecting the GABAergic system.