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66193-59-7

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66193-59-7 Usage

Description

1-Naphthalenecarboxylic acid, 5,6,7,8-tetrahydro-, methyl ester, also known as Methyl 5,6,7,8-tetrahydronaphthalene-1-carboxylate, is an organic compound derived from naphthalene. It is characterized by its ester functional group and a tetrahydronaphtalene ring structure. 1-Naphthalenecarboxylic acid, 5,6,7,8-tetrahydro-, methyl ester is known for its potential applications in the pharmaceutical industry due to its unique chemical properties.

Uses

1. Used in Pharmaceutical Industry:
1-Naphthalenecarboxylic acid, 5,6,7,8-tetrahydro-, methyl ester is used as an intermediate compound for the synthesis of Palonosetron (P165830), a serotonin 5-HT3 receptor antagonist. Palonosetron is specifically utilized in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). 1-Naphthalenecarboxylic acid, 5,6,7,8-tetrahydro-, methyl ester's ability to interact with serotonin receptors makes it a valuable component in the development of antiemetic medications.
2. Used in Drug Development:
As a key intermediate in the synthesis of Palonosetron, 1-Naphthalenecarboxylic acid, 5,6,7,8-tetrahydro-, methyl ester plays a crucial role in drug development. Its unique chemical structure allows for the creation of targeted therapies that can help alleviate the side effects of chemotherapy, improving the quality of life for cancer patients undergoing treatment.

Check Digit Verification of cas no

The CAS Registry Mumber 66193-59-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,1,9 and 3 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 66193-59:
(7*6)+(6*6)+(5*1)+(4*9)+(3*3)+(2*5)+(1*9)=147
147 % 10 = 7
So 66193-59-7 is a valid CAS Registry Number.

66193-59-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl 5,6,7,8-tetrahydronaphthalene-1-carboxylate

1.2 Other means of identification

Product number -
Other names 1-Naphthalenecarboxylic acid,5,6,7,8-tetrahydro-,methyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:66193-59-7 SDS

66193-59-7Relevant articles and documents

C-GLUCOSIDE DERIVATIVE CONTAINING FUSED PHENYL RING OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PROCESS FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

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Paragraph 0186-0187, (2018/12/04)

The present disclosure relates to C-glycoside derivatives having a fused phenyl ring or pharmaceutical acceptable salts thereof, a method for preparing the same, a pharmaceutical composition comprising the same, a use thereof and a method for dual inhibition of SGLT1 and SGLT2 using the same. A novel compound of the present disclosure has a dual inhibitory activity against SGLT1 and SGLT2, thus being valuably used as a diabetes therapeutic agent.

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