66362-95-6

Basic information

• Product Name: 2-Pyridinamine, 5-methyl-, 1-oxide
• Synonyms: 2-Pyridinamine, 5-methyl-, 1-oxide;1-hydroxy-5-methylpyridin-1-ium-2-amine
• CAS NO: 66362-95-6
• Molecular Formula: C6H8N2O
• Molecular Weight: 124.14
• Product Categories: pharmacetical
• Mol File: 66362-95-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 382.7°C at 760 mmHg
• Flash Point: 185.3°C
• Appearance: /
• Density: 1.18g/cm³
• Vapor Pressure: 4.63E-06mmHg at 25°C
• Refractive Index: 1.569
• CAS DataBase Reference: 2-Pyridinamine, 5-methyl-, 1-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinamine, 5-methyl-, 1-oxide(66362-95-6)
• EPA Substance Registry System: 2-Pyridinamine, 5-methyl-, 1-oxide(66362-95-6)

Safety Data

• Hazardous Substances Data: 66362-95-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H8N2O/c1-5-2-3-6(7)8(9)4-5/h2-4H,7H2,1H3

Upstream product

• 41322-67-2 (5-methyl-pyridin-2-yl)-carbamic acid ethyl ester 
• 1603-41-4 (5-methyl-pyridin-2-yl)amine 
• 103860-34-0 5-Methl-2-ethoxycarbonylamino-pyridin-N-oxid 
• 79-21-0 peracetic acid 
• 4931-47-9 N-(5-methylpyridin-2-yl)acetamide 

Downstream Products

• 20173-49-3 2-chloro-5-methylpyridine-N-oxide 

Relevant articles and documents

Ligand compound for copper catalyzed aryl halide coupling reaction, catalytic system and coupling reaction

The invention provides a ligand compound capable of being used for copper catalyzed aryl halide coupling reaction, the ligand compound is a three-class compound containing a 2-(substituted or non-substituted) aminopyridine nitrogen-oxygen group, and the invention also provides a catalytic system for the aryl halide coupling reaction. Thecatalytic system comprises a copper catalyst, a compound containing a 2-(substituted or non-substituted) aminopyridine nitrogen-oxygen group adopted as a ligand, alkali and a solvent, and meanwhile, the invention also provides a system for the aryl halide coupling reaction adopting the catalyst system. The compound containing the 2-(substituted or non-substituted) aminopyridine nitrogen oxygen group can be used as the ligand for the copper catalyzed aryl chloride coupling reaction, and the ligand is stable under a strong alkaline condition and can well maintain catalytic activity when being used for the copper-catalyzed aryl chloride coupling reaction. In addition, the copper catalyst adopting the compound as the ligand can particularly effectively promote coupling of copper catalyzed aryl chloride and various nucleophilic reagents which are difficult to generate under conventional conditions, C-N, C-O and C-S bonds are generated, and numerous useful small molecule compounds are synthesized. Therefore, the aryl halide coupling reaction has a very good large-scale application prospect by adopting the copper catalysis system of the ligand.

Cosmetic composition for imparting to human skin a coloration resembling a natural tan

A cosmetic composition for imparting to human skin after exposure to sunlight a coloration resembling a natural tan comprising a cosmetic vehicle suitable for topical application to the skin and an effective amount of at least one compound of the formula STR1 wherein R1 represents hydrogen or amino; R2 represents hydrogen, lower alkyl or amino; R3 represents hydrogen, lower alkyl or amino; R4 represents hydrogen, lower alkyl or chlorine; and R5 represents hydrogen, lower alkyl or hydroxy, or amino when R1 is amino, with the proviso that R1, R2 and R3 are not simultaneously amino; and at least one of R1, R2 R3 means amino or an acid addition salt thereof.