66469-86-1

Basic information

• Product Name: ETHYL 2,5-DIMETHOXYPHENYLACETATE
• Synonyms: ETHYL 2,5-DIMETHOXYPHENYLACETATE;HOMOGENTISIC ACID ETHYL ESTER;Ethyl 2-(2,5-dimethoxyphenyl)acetate
• CAS NO: 66469-86-1
• Molecular Formula: C₁₂H₁₆O₄
• Molecular Weight: 224.25
• Product Categories: Aromatic Phenylacetic Acids and Derivatives;C12 to C63;Carbonyl Compounds;Esters
• Mol File: 66469-86-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 162-165 °C8 mm Hg(lit.)
• Flash Point: 160 °F
• Appearance: /
• Density: 1.12 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.000633mmHg at 25°C
• Refractive Index: n20/D 1.513(lit.)
• CAS DataBase Reference: ETHYL 2,5-DIMETHOXYPHENYLACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 2,5-DIMETHOXYPHENYLACETATE(66469-86-1)
• EPA Substance Registry System: ETHYL 2,5-DIMETHOXYPHENYLACETATE(66469-86-1)

Safety Data

• RIDADR: NA 1993 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 66469-86-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H16O4/c1-4-16-12(13)8-9-7-10(14-2)5-6-11(9)15-3/h5-7H,4,8H2,1-3H3

Upstream product

• 64-17-5 ethanol 
• 52711-92-9 2,5-dimethoxyphenylacetyl chloride 
• 1758-25-4 (2,5-dimethoxyphenyl)acetic acid 
• 1201-38-3 2',5'-dimethoxyacetophenone 
• 6202-39-7 homogentisic acid methyl ester dimethyl ether 
• 129667-23-8 ethyl 2-chloro-2-(butylthio)acetate 
• 150-78-7 1,4-dimethoxybezene 
• 18086-24-3 2-(2,5-dimethoxyphenyl)acetonitrile 
• 116632-49-6 (2,5-dimethoxy-phenyl)-pyruvic acid 

Downstream Products

• 710324-46-2 3-(2,4-Dichloro-pyrimidin-5-yl)-2-(2,5-dimethoxy-phenyl)-propionic acid ethyl ester 
• 66397-42-0 Ethyl-2.6-dimethyl-8-(2'.5'-dimethoxyphenyl)octa-2E_.6E-dienoat 
• 50628-18-7 2,6-dimethyl-8-(2,5-dimethoxyphenyl)octa-2,6-dienal 
• 66397-43-1 8-(2,5-dimethoxyphenyl)-2,6-dimethylocta-2,6-dienol 
• 66397-40-8 2-Methyl-3-vinyloxy-4-(2',5'-dimethoxyphenyl)-but-1-en 
• 66397-39-5 2-Methyl-3-hydroxy-4-(2',5'-dimethoxyphenyl)-but-1-en 
• 33567-62-3 2-(2,5-dimethoxyphenyl)acetaldehyde 
• 99187-42-5 2-(2,5-dimethoxyphenyl)ethylbromide 
• 76196-47-9 ethyl (1,4-benzoquinolyl)acetate 
• 767264-65-3 (+/-)-3-(2,5-dimethoxyphenyl)piperidine 
• 150129-95-6 (+/-)-3-(2,5-dimethoxyphenyl)piperidin-2-one 
• 7417-19-8 2-(2,5-dimethoxyphenyl)ethanol 

Relevant articles and documents

1,2-disubstituted-6-oxo-3-phenyl-piperidine-3-carboxamides and combinatorial libraries thereof

The invention relates to combinatorial libraries containing two or more novel piperidine-3-carboxamide derivative compounds, methods of preparing the piperidine-3-carboxamide derivative compounds and piperidine-3-carboxamide derivative compounds bound to a resin

Organic Synthesis with α-Chloro Sulphides. Preparation of Aromatic γ-Lactones from Phenols and α-Chloro Sulphide Carboxylates

Lewis acid-catalysed alkylation of para-substituted phenols using α-chloro sulphides as electrophiles yields sulphenylated γ-lactones which can be desulphurised with zinc in acetic acid or Raney nickel.This synthesis has been applied to p-cresol, 2-naphthol, and two phenolic dihydrocinnamates.Alkylation of 1,4-dimethoxybenzene yields homogentisic acid dimethyl ether after desulphurisation and hydrolysis.