664999-61-5

Basic information

• Product Name: 2-amino-6-(hydroxymethyl)-4-(3-methoxyphenyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carbonitrile
• Synonyms: 2-amino-6-(hydroxymethyl)-4-(3-methoxyphenyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carbonitrile
• CAS NO: 664999-61-5
• Molecular Formula: C₁₇H₁₄N₂O₅
• Molecular Weight: 326.30346
• Mol File: 664999-61-5.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-amino-6-(hydroxymethyl)-4-(3-methoxyphenyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-6-(hydroxymethyl)-4-(3-methoxyphenyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carbonitrile(664999-61-5)
• EPA Substance Registry System: 2-amino-6-(hydroxymethyl)-4-(3-methoxyphenyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carbonitrile(664999-61-5)

Safety Data

• Hazardous Substances Data: 664999-61-5(Hazardous Substances Data)

Usage

Structure

Contains a pyrano-pyran backbone, a carbonitrile moiety, an amino group, and a hydroxymethyl group

Type

Heterocyclic compound

Potential Activities

Biological and pharmacological

Functional Groups

Amino and hydroxymethyl

Potential Applications

Medicinal chemistry, drug discovery, development of new therapeutic agents

Need for Further Research

Additional characterization to determine full potential and properties

Upstream product

• 501-30-4 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 
• 591-31-1 3-methoxy-benzaldehyde 
• 109-77-3 malononitrile 
• 2972-72-7 2-(3-methoxybenzylidene)malononitrile 

Relevant articles and documents

The first efficient biocatalytic route for the synthesis of Kojic acid derivatives in aqueous media

The first efficient biocatalytic route for the synthesis of kojic acid derivatives was developed in presence of an enzyme. In this process, benzaldehydes, malononitrile and kojic acid were used as starting materials while lipase from Aspergillus niger was

Acetic Acid-Mediated Synthesis of Kojic Acid Derivatives

Abstract: A green acetic acid-mediated synthesis of kojic acid derivatives through amulticomponent reaction (MCR) has been developed. This new protocol is simpleand efficient; it involves a one-pot reaction of equimolar amounts of kojicacid, aromatic alde

One-pot synthesis of 2-amino-4,8-dihydropyrano[3,2-b]pyranes and pyridopyrimidines under mild conditions

1,8-Diazabicyclo[5.4.0]undec-7-ene immobilized on silica (SB-DBU)Cl as a reusable and heterogeneous catalyst was applied for the one-pot, three-component synthesis of 2-amino-4,8-dihydropyrano[3,2-b]pyrane-3-carbonitriles and pyridopyrimidines, under solvent-free conditions. The reaction was carried out at room temperature, and pure products were obtained in high yields and short reaction times (3–7 min). This work introduced an environmentally benign procedure for the synthesis of these classes of biological active compounds.