6698-72-2

Basic information

• Product Name: 1-(4-NITROPHENOXY)-2-PROPANONE
• Synonyms: 1-(4-NITROPHENOXY)-2-PROPANONE
• CAS NO: 6698-72-2
• Molecular Formula: C₉H₉NO₄
• Molecular Weight: 195.17
• Mol File: 6698-72-2.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 341.8°C at 760 mmHg
• Flash Point: 166.2°C
• Appearance: /
• Density: 1.255g/cm³
• Vapor Pressure: 7.83E-05mmHg at 25°C
• Refractive Index: 1.54
• CAS DataBase Reference: 1-(4-NITROPHENOXY)-2-PROPANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-NITROPHENOXY)-2-PROPANONE(6698-72-2)
• EPA Substance Registry System: 1-(4-NITROPHENOXY)-2-PROPANONE(6698-72-2)

Safety Data

• Hazardous Substances Data: 6698-72-2(Hazardous Substances Data)

Usage

Synonym

PPNP

Physical state

Yellow crystalline solid

Usage

Research and industrial applications

Function

Reagent for the synthesis of various organic compounds

Chemical property

Ability to undergo nucleophilic addition reactions

Applications

Preparation of pharmaceuticals, agrochemicals, and other fine chemicals

Hazard classification

Classified as a hazardous substance

Health hazards

Can cause irritation to the skin, eyes, and respiratory system upon exposure

Safety precautions

Handle with care and store in accordance with relevant safety guidelines and regulations

InChI:InChI=1/C9H9NO4/c1-7(11)6-14-9-4-2-8(3-5-9)10(12)13/h2-5H,6H2,1H3

Upstream product

• 100-02-7 4-nitro-phenol 
• 78-95-5 chloroacetone 
• 28341-54-0 4-(4-nitrophenoxy)butanoic acid 
• 1124-31-8 potassium 4-nitrophenolate 
• 28210-59-5 potassium p-nitrophenolate monohydrate 
• 10572-15-3 propylene glycol-α-(4-nitro-phenyl ether ) 
• 824-78-2 4-nitrophenol sodium salt 
• 1666-18-8 4-Chlor-benzolsulfonsaeure-acetolester 
• 2684-62-0 diazoacetone 
• 17061-85-7 1-nitro-4-(prop-2-ynyloxy)benzene 
• 67-64-1 acetone 

Downstream Products

• 859466-10-7 4-(4-nitrophenoxymethyl)-2-aminothiazole 
• 850852-87-8 4-methyl-5-(4-nitro-phenoxy)-thiazol-2-ylamine 
• 74094-71-6 1-bromo-3-(4-nitro-phenoxy)-acetone 
• 99807-07-5 (4-amino-phenoxy)-acetone 
• 100-02-7 4-nitro-phenol 
• 157028-14-3 1-(4-aminophenoxy)propan-2-one hydrochloride 
• 118077-75-1 2-methyl-2-(4-nitrophenoxymethyl)-4-oxochroman 
• 118077-81-9 6-fluoro-2-methyl-2-(4-nitrophenoxymethyl)-4-oxochroman 
• 1294011-03-2 ethyl 2-amino-4-methyl-5-(4-nitrophenoxy)thiophene-3-carboxylate 
• 1452849-38-5 1-(4-(6,7-dimethoxy-2-methylquinolin-3-yloxy)phenyl)-3-p-tolylurea 
• 1452849-37-4 1-(4-(6,7-dimethoxy-2-methylquinolin-3-yloxy)phenyl)-3-phenylurea 

Relevant articles and documents

TBAI/TBHP mediated oxidative cross coupling of ketones with phenols and carboxylic acids: Direct access to benzofurans

TBAI/TBHP mediated oxidative cross coupling of phenols and carboxylic acids with ketones has been reported under metal-free, base free, solvent free conditions enabling environmentally benign synthesis of aryloxyketones, acyloxy ketones and benzofurans. Phenoxyketones and acyloxylcarbonyl compounds were synthesized in good to high yields, where as benzofurans were synthesized in moderate yields. This method is operationally simple, works under mild conditions, using commercially available as well as inexpensive TBAI and an oxidant TBHP.

METHOD FOR PRODUCING PYRIMIDINE-1-OL COMPOUND, AND INTERMEDIATE THEREOF

There are provided a method for producing 2,4-disubstituted pyrimidine-5-ol, and particularly, 2,4-dimethylpyrimidine-5-ol and an intermediate thereof used in industrial production. The production method according to the present invention includes a step

Linear Free Energy Correlation Analysis on the Electronic Effects of Rh(II) Carbene O-H Insertion

The relative rate constants for the Rh(II)-catalyzed insertion of diazoacetone into the O-H bond have been measured through intermolecular competitions. The kinetic data were subjected to Hammett correlation analysis, and mechanistic implication of the results with respect to a stepwise vs a concerted O-H insertion pathway is discussed.