859466-10-7

Basic information

• Product Name: 4-(4-nitrophenoxymethyl)-2-aminothiazole
• Synonyms: 4-(4-nitrophenoxymethyl)-2-aminothiazole
• CAS NO: 859466-10-7
• Molecular Weight: 251.266
• Mol File: 859466-10-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(4-nitrophenoxymethyl)-2-aminothiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-nitrophenoxymethyl)-2-aminothiazole(859466-10-7)
• EPA Substance Registry System: 4-(4-nitrophenoxymethyl)-2-aminothiazole(859466-10-7)

Safety Data

• Hazardous Substances Data: 859466-10-7(Hazardous Substances Data)

Upstream product

• 6698-72-2 1-(4-nitrophenoxy)propan-2-one 
• 74094-71-6 1-bromo-3-(4-nitro-phenoxy)-acetone 
• 17356-08-0 thiourea 
• 1124-31-8 potassium 4-nitrophenolate 
• 1616562-84-5 1-[(2-azidoallyl)oxy]-4-nitrobenzene 
• 1147550-11-5 ammonium thiocyanate 

Relevant articles and documents

Visible-Light-Driven Synthesis of 4-Alkyl/Aryl-2-Aminothiazoles Promoted by in Situ Generated Copper Photocatalyst

Room-temperature synthesis of 4-alkyl/aryl-2-aminothiazoles from vinyl azides and ammonium thiocyanate was accomplished with the aid of copper salts and blue LED irradiation. Mechanism investigation indicates that in situ-formed Cu(NCS)2- plays dual important roles in the reaction: (1) as the photocatalyst to activate vinyl azides, (2) as the Lewis acid catalyst to promote ring opening of 2H-azirines with thiocyanide. This process is distinguished by high yields, mild conditions, low catalyst loadings, and tolerating numerous alkyl- and aryl vinyl azides with an array of functional groups.