67035-94-3 Usage
Description
DIETHYL MALONATE-2-13C, also known as the labeled form of Diethyl Malonate (D444420), is a naturally occurring compound found in grapes and strawberries. It is characterized by the presence of a 13C isotope, which distinguishes it from the non-labeled version of the compound. This unique feature makes it valuable for various applications in different industries.
Uses
Used in Pharmaceutical Industry:
DIETHYL MALONATE-2-13C is used as an intermediate compound for the synthesis of various pharmaceutical products, including barbiturates, which are central nervous system depressants. Its labeled nature allows for better tracking and analysis of the compound during the synthesis process, ensuring the production of high-quality and effective medications.
Used in Flavor and Fragrance Industry:
DIETHYL MALONATE-2-13C is used as a key component in the preparation of artificial flavorings and perfumes. Its unique properties and labeled nature make it an ideal candidate for creating distinct and long-lasting scents, enhancing the sensory experience of consumers.
Used in Vitamin Production:
DIETHYL MALONATE-2-13C is utilized in the production of essential vitamins, such as vitamin B1 (thiamine) and vitamin B6 (pyridoxine). Its incorporation into the synthesis process helps ensure the efficient and accurate production of these vital nutrients, which play crucial roles in maintaining overall health and well-being.
Check Digit Verification of cas no
The CAS Registry Mumber 67035-94-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,0,3 and 5 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 67035-94:
(7*6)+(6*7)+(5*0)+(4*3)+(3*5)+(2*9)+(1*4)=133
133 % 10 = 3
So 67035-94-3 is a valid CAS Registry Number.
67035-94-3Relevant articles and documents
A Facile One-Step Synthesis of Diethyl Malonate from Ethyl Acetate
Mueller, Mark E.,Leete, Edward
, p. 3151 - 3152 (1981)
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A convenient synthesis of 4-hydroxy[1-13c]benzoic acid and related ring-labelled phenolic compounds
Beyer, Jürgen,Lang-Fugmann, Susanne,Mühlbauer, Andrea,Steglich, Wolfgang
, p. 1047 - 1051 (2007/10/03)
4-Hydroxy[1-13C]benzoic acid (5) was synthesized starting from commercially available sodium [2-13C]acetate (1) by a 4-step sequence in an overall yield of 55-65%. Key step in this synthesis is the formation of the benzene ring by base-catalyzed condensation of diethyl [2-13C]malonate (3) with 4H-pyran-4-one. Acid 5 or its ethyl ester could be converted into 3,4- dihydroxy[1-13C]benzoic acid (9), D,L-[1'-13C]tyrosine (14) and 1,2,4- trihydroxy[4-13C]benzene (19) with high efficiency.
