672963-94-9

Basic information

• Product Name: 4(5H)-Oxazolone, 2-phenyl-5-(phenylmethyl)-
• CAS NO: 672963-94-9
• Molecular Formula: C16H13NO2
• Molecular Weight: 251.285
• Mol File: 672963-94-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4(5H)-Oxazolone, 2-phenyl-5-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4(5H)-Oxazolone, 2-phenyl-5-(phenylmethyl)-(672963-94-9)
• EPA Substance Registry System: 4(5H)-Oxazolone, 2-phenyl-5-(phenylmethyl)-(672963-94-9)

Safety Data

• Hazardous Substances Data: 672963-94-9(Hazardous Substances Data)

Upstream product

• 55-21-0 benzamide 
• 150-30-1 Phenylalanine 
• 63-91-2 L-phenylalanine 
• 16503-53-0 2-bromo-3-phenylpropanoic acid 
• 81136-07-4 2-bromo-3-phenylpropionyl chloride 
• 672963-83-6 N-benzoyl-2-bromo-3-phenylpropanamide 

Downstream Products

• 1402230-61-8 C₃₂H₂₉N₂O₃P 
• 1402230-46-9 C₃₆H₃₁N₂O₃P 
• 1402230-71-0 C₃₆H₃₁N₂O₃P 

Relevant articles and documents

Non-hydrogen bond catalyst-mediated diastereoselective conjugate additions of 5: H -oxazol-4-ones to o -hydroxyphenyl-substituted p -quinone methides

An efficient DBU-catalyzed conjugate addition of 5H-oxazol-4-ones to o-hydroxyphenyl-substituted p-quinone methides has been developed, affording the valuable diarylmethanes in high yields with excellent diastereoselectivity. This strategy demonstrates a robust access to a wide range of diarylmethane derivatives possessing biologically significant o-hydroxyphenol and p-hydroxyphenol moieties under mild reaction conditions.

5H-Oxazol-4-ones as Building Blocks for Asymmetric Synthesis of α-Hydroxycarboxylic Acid Derivatives

5H-Alkyl-2-phenyl-oxazol-4-ones, a little-known heterocyclic ring system, are readily available via a microwave-assisted, sodium fluoride catalyst cyclization of mono-α-haloimides, which in turn are accessed by N-acylation of benzamides with α-bromo acid