67473-36-3 Usage
Description
17 alpha-cyanomethyl-19-nortestosterone, also known as 17α-Cyanomethyl-19-nor-17β-hydroxygon-4-en-3-one, is a synthetic steroid derived from the modification of the naturally occurring hormone testosterone. It is a metabolite of Norethindrone, a synthetic progestin used in the pharmaceutical industry.
Uses
Used in Contraceptive Applications:
17 alpha-cyanomethyl-19-nortestosterone is used as a contraceptive agent in combination with estrogen. It serves as a synthetic progestin, which helps prevent ovulation and alters the cervical mucus to inhibit sperm penetration, thereby providing a reliable method of birth control.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 17 alpha-cyanomethyl-19-nortestosterone is used as a key intermediate in the synthesis of various progestational agents. These agents are essential components in the development of hormonal contraceptives and other medications related to reproductive health.
Check Digit Verification of cas no
The CAS Registry Mumber 67473-36-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,4,7 and 3 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 67473-36:
(7*6)+(6*7)+(5*4)+(4*7)+(3*3)+(2*3)+(1*6)=153
153 % 10 = 3
So 67473-36-3 is a valid CAS Registry Number.
InChI:InChI=1/C20H27NO2/c1-19-8-6-16-15-5-3-14(22)12-13(15)2-4-17(16)18(19)7-9-20(19,23)10-11-21/h12,15-18,23H,2-10H2,1H3/t15-,16+,17+,18-,19-,20?/m0/s1
67473-36-3Relevant articles and documents
Process for the production of unsaturated 17 α-cyanomethyl-17 β-h
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, (2008/06/13)
The unsaturated 17α-cyanomethyl-17β-hydroxy steroids of the formula I, STR1 in which R 1 =Me, Eth; R 2 =H, Me; R 3 =H, OH, an acetoxy or alkoxy group; R 4 =H, R 5 =OH, an acetoxy, alkoxy group of R 4 and R 5 together represent a keto- or ketal group and double bonds are contained in the basic structure of the steroid, particularly between the 15 and 16 position in the steroid ring, from unsaturated 17-ketosteroids of the general formula II as described herein with the aforementioned meanings of R 1 to R 5 by reacting the unsaturated 17-ketosteroids with LiCH 2 CN and subsequently hydrolyzing.The compounds of formula I are pharmacologically interesting steroid compounds or also intermediate products for the synthesis of highly-effective steroid products which can be used in human and veterinary medicine for the treatment of endocrine disorders and for reproductive control based on their specific hormonal/anti-hormonal actions.The compounds are suitable for the treatment of endometriosis and also in combination with preparations with ethinylestradiol for fertility control.
