83807-35-6

Basic information

• Product Name: 17α-Cyanomethyl-5α-estran-3α,17β-diol
• CAS NO: 83807-35-6
• Molecular Weight: 317.472
• Mol File: 83807-35-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 17α-Cyanomethyl-5α-estran-3α,17β-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 17α-Cyanomethyl-5α-estran-3α,17β-diol(83807-35-6)
• EPA Substance Registry System: 17α-Cyanomethyl-5α-estran-3α,17β-diol(83807-35-6)

Safety Data

• Hazardous Substances Data: 83807-35-6(Hazardous Substances Data)

Upstream product

• 67473-36-3 17α-Cyanomethyl-17β-hydroxyestr-4-en-3-one 

Relevant articles and documents

MICROBIAL TRANSFORMATION OF 17α-CYANOMETHYL-17-HYDROXY-4,9-ESTRADIEN-3-ONE (STS 557) AND 17α-CYANOMETHYL-19-NORTESTOSTERONE BY MYCOBACTERIUM SMEGMATIS

Microbial transformation of the new progestagen STS 557 (17α-cyanomethyl-17-hydroxy-4,9-estradien-3-one) by Mycobacterium smegmatis yielded predominantly ring A-aromatized compounds. 17α-cyanomethyl-1,3,5(10),9(11)-estratetraene-3,17-diol, 17α-cyanomethyl-1,3,5(10)-estratriene-3,17-diol and the corresponding 3-methyl ethers.The analogous compound without the 9(10) double bound, 17α-cyanomethyl-19-nortestosterone, was transformed mainly to 5α-hydrogenated metabolites: 17α-cyanomethyl-17-hydroxy-5α-estran-3-one, 17α-cyanomethyl-17-hydroxy-5α-1-estren-3-one, 17α-cyanomethyl-5α-estrane-3α,17-diol, and 17α-cyanomethyl-5α-estrane- 3β,17-diol.From these results, it is concluded that 4,9-dien-3-oxo compounds are not substrates for enzymatic 5α-hydrogenation.