6772-72-1

Basic information

• Product Name: 2-(4-methoxy-phenyl)-1,4-dihydro-2H-isoquinolin-3-one
• CAS NO: 6772-72-1
• Molecular Weight: 253.301
• Mol File: 6772-72-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-methoxy-phenyl)-1,4-dihydro-2H-isoquinolin-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methoxy-phenyl)-1,4-dihydro-2H-isoquinolin-3-one(6772-72-1)
• EPA Substance Registry System: 2-(4-methoxy-phenyl)-1,4-dihydro-2H-isoquinolin-3-one(6772-72-1)

Safety Data

• Hazardous Substances Data: 6772-72-1(Hazardous Substances Data)

Upstream product

• 4385-35-7 isochroman-3-one 
• 104-94-9 4-methoxy-aniline 

Relevant articles and documents

Synthetic approaches to 2-substituted 1-oxo- and 3-oxotetrahydroisoquinolines

2-Substituted homophthalimides 2a-c were reduced regioselectively with sodium borohydride to carbinol-lactam intermediates 3a-c, which were dehydrated, followed by hydrogenation, to give 1-oxotetrahydroisoquinolines or 3,4-dihydroisoquinolin-1(2H)ones 5a-c. The isomeric 3-oxo-tetrahydroisoquinolines or 1,4-dihydroisoquinolin-3(2H)-ones 8a-i were obtained in satisfactory yields via heating 3-isochromanone (6) with the corresponding amines 7a-i in the presence of aluminum chloride.