6786-09-0

Basic information

• Product Name: (3α)-Cholic acid amide
• Synonyms: (3α)-Cholic acid amide;3α,7α,12α-Trihydroxy-5β-cholan-24-amide;3α,7α,12α-Trihydroxy-5β-cholan-24-oic amide;Cholamide【steroid】
• CAS NO: 6786-09-0
• Molecular Formula: C₂₄H₄₁NO₄
• Molecular Weight: 407.58664
• Mol File: 6786-09-0.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3α)-Cholic acid amide(CAS DataBase Reference)
• NIST Chemistry Reference: (3α)-Cholic acid amide(6786-09-0)
• EPA Substance Registry System: (3α)-Cholic acid amide(6786-09-0)

Safety Data

• Hazardous Substances Data: 6786-09-0(Hazardous Substances Data)

Upstream product

• 1448-36-8 methyl cholate 
• 2216-51-5 (-)-menthol 
• 81-25-4 cholic acid 
• 74670-08-9 (3α,5β,7α,12α)-3,7,12-tris(formyloxy)cholan-24-oyl chloride 
• 7664-41-7 ammonia 
• 475-31-0 glycocholic acid 
• 111823-93-9 3α,7α,12α-tris-formyloxy-5β-cholan-24-oic acid amide 
• 40248-73-5 3α,7α,12α-trihydroxy-5β-cholanoyl-(24)-azide 

Downstream Products

• 2458-08-4 3α,7α-dihydroxy-12-oxo-5β-cholan-24-oic acid 
• 474-25-9 chenodeoxycholic acid 

Relevant articles and documents

Anion Selective Ion Channel Constructed from a Self-Assembly of Bis(cholate)-Substituted Fumaramide

The self-assembled ion channel constructed from bis(cholate)-substituted fumaramide is reported. Such ion channel formation was favored by intermolecular hydrogen bonding interactions among fumaramide moieties. Fluorescence kinetics experiments and planar bilayer conductance measurements confirmed the selective chloride transport through the channel. Theoretical calculations were done to confirm the hydrogen bonded self-assembly of fumaramides and chloride recognition within the cavity.

Study on the structure-activity relationship of dihydroartemisinin derivatives: Discovery, synthesis, and biological evaluation of dihydroartemisinin-bile acid conjugates as potential anticancer agents

A series of dihydroartemisinin derivatives was synthesized, and their anti-proliferation activity against cancer cells was evaluated. Structure-activity relationship studies led to the discovery of dihydroartemisinin-bile acid conjugates that exhibit broa

Anti-Diabetic Compounds

The preset invention relates to a new oral anti-diabetic compound prepared by synthesizing a steroid and a guanide or biguanide, which is eliminated via the hepatic route, instead of the renal route, to avoid adverse effects of Metformin, such as renal dysfunction. A pharmaceutical composition comprising the compound of the invention and the method for treating diabetes using the compound are also provided.