679410-96-9Relevant articles and documents
A new series of estrogen receptor modulators: Effect of alkyl substituents on receptor-binding affinity
Kamada, Atsushi,Sasaki, Atsushi,Kitazawa, Noritaka,Okabe, Tadashi,Nara, Kazumasa,Hamaoka, Shinichi,Araki, Shin,Hagiwara, Hiroaki
, p. 79 - 88 (2007/10/03)
New types of selective estrogen receptor modulators (SERMs) were synthesized and evaluated for their binding affinity and biological effect on reproductive cells. A proposed lead structure (B) was derivatized to provide compounds 30 and 44, which showed g