68141-13-9

Basic information

• Product Name: 6-TERT-BUTYLQUINOLINE
• Synonyms: 6-(1,1-dimethylethyl)-quinolin;6-(1,1-dimethylethyl)-Quinoline;6-TERT-BUTYLQUINOLINE;6-tert-Butylchinolin;6-TERT-BUTYLQUINOLINE,98.0+%(GC)(T);Einecs 268-835-5;Quinoline, 6-(1,1-dimethylethyl)-;6-tert-Butylquinoline
• CAS NO: 68141-13-9
• Molecular Formula: C₁₃H₁₅N
• Molecular Weight: 185.26
• EINECS: 268-835-5
• Product Categories: Alkylquinolines;Quinolines
• Mol File: 68141-13-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 286.2 °C at 760 mmHg
• Flash Point: 116.3 °C
• Appearance: /
• Density: 1.01
• Vapor Pressure: 0.00462mmHg at 25°C
• Refractive Index: 1.5820-1.5860
• CAS DataBase Reference: 6-TERT-BUTYLQUINOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-TERT-BUTYLQUINOLINE(68141-13-9)
• EPA Substance Registry System: 6-TERT-BUTYLQUINOLINE(68141-13-9)

Safety Data

• Hazardous Substances Data: 68141-13-9(Hazardous Substances Data)

Usage

General Description

6-Tert-butylquinoline is a chemical compound with the molecular formula C16H17N. It is a quinoline derivative and is used as a corrosion inhibitor and as an intermediate in the synthesis of pharmaceuticals and other organic compounds. It is a yellow-brown liquid with a characteristic odor and is insoluble in water but soluble in most organic solvents. It is commonly used in the production of rubber, plastics, and other industrial products and is also utilized in research and development laboratories for various applications. It is important to handle 6-tert-butylquinoline with caution due to its potential health and environmental hazards.

InChI:InChI=1/C13H15N/c1-13(2,3)11-6-7-12-10(9-11)5-4-8-14-12/h4-9H,1-3H3

Upstream product

• 769-92-6 4-tert-Butylaniline 
• 56-81-5 glycerol 
• 127-68-4 sodium 3-nitrobenzenesulfonate 
• 504-63-2 trimethyleneglycol 
• 3282-56-2 4-tert-butylnitrobenzene 

Downstream Products

• 1609198-99-3 6-(tert-butyl)-4-(1-phenylethyl)quinoline 
• 1609199-06-5 C₂₁H₂₃N 
• 958328-02-4 6-tert-butyl-N-((1R)-1-{3-methyl-4[(methylsulfonyl)amino]phenyl}-ethyl)quinoline-2-carboxamide 
• 958328-21-7 6-TERT-BUTYL-N-((1R)-1-{2-FLUORO-5-METHYL-4-[(METHYLSULFONYL)AMINO]PHENYL}-ETHYL)QUINOLINE-2-CARBOXAMIDE 
• 75413-98-8 6-t-butyl-1,2,3,4-tetrahydroquinoline 
• 75414-04-9 6-tert-butyl-5,6,7,8-tetrahydroquinoline 

Relevant articles and documents

Mild environment-friendly oxidative debenzylation of N-benzylanilines using DMSO as an oxidant

Oxidative debenzylation of N-benzyl aromatic amines using DMSO as a non-toxic oxidant and catalyzed by TsOH gave Nphenylimines, which were spontaneously hydrolyzed to form anilines and benzaldehydes in good yields. This reaction employs mild, metal-free conditions. The conditions are also suitable for the debenzylation of benzylphenylethers.

Highly Enantioselective Direct Synthesis of Endocyclic Vicinal Diamines through Chiral Ru(diamine)-Catalyzed Hydrogenation of 2,2′-Bisquinoline Derivatives

An asymmetric hydrogenation of 2,2′-bisquinoline and bisquinoxaline derivatives, catalyzed by chiral cationic ruthenium diamine complexes, was developed. A broad range of chiral endocyclic vicinal diamines were obtained in high yields with excellent diastereo- and enantioselectivity (up to 93:7 dl/meso and >99 % ee). These chiral diamines could be easily transformed into a new class of chiral N-heterocyclic carbenes (NHCs), which are important but difficult to access.

Amino-substituted imidazo[1,2-a:3,4-a']diquinolin-15-ium salts compositions and method of use

Amino-substituted imidazo[1,2-a:3,4-a']diquinolin-15-ium salts having the formula I: STR1 wherein R1 is hydrogen, lower alkyl, C4 -C6 cycloalkyl, di(lower alkyl)amino, 1-azetidinyl, 1-pyrrolidinyl, 1-piperidinyl, methyl-1-pyrrolidinyl, methyl-1-piperidinyl, 4-morpholinyl or 2,2-dimethylhydrazino; R2 is hydrogen, lower alkyl, lower alkylamino, di(lower alkyl)amino, C4 -C6 cycloalkylamino, lower alkoxy(lower alkyl)amino, 1-azetidinyl, 1-pyrrolidinyl, 1-piperidinyl, methyl-1-pyrrolidinyl, methyl-1-piperidinyl, hexahydro-1H-azepin-1-yl, 4-morpholinyl, benzylamino, N-methylbenzylamino or 2-phenylethylamino; R3 is hydrogen or methyl; X is an anion; with the proviso that at least one of R1 and R2 is other than hydrogen, lower alkyl or C4 -C6 cycloalkyl; and with the further proviso that when R2 is dimethylamino, at least one of R1 and R3 is other than hydrogen, and intermediates used in the preparation thereof are disclosed. The compounds of the invention are prepared by amination of the corresponding chloro or fluoro-substituted imidazo [1,2-a:3,4-a']diquinolin-15-ium salts; either the halo substituted intermediates or the amino substituted salts may be further treated, typically using ion exchange techniques to obtain a variety of physiologically acceptable amino-substituted [1,2-a:3,4-a']diquinolin-15-ium salts which exhibit antifungal activity.