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681853-95-2

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  • SAGECHEM/2-(tert-butyldiphenylsilyloxy)-1-((4S,5S)-2,2-dimethyl-5-vinyl-1,3-dioxolan-4-yl)ethanone/SAGECHEM/Manufacturer in China

    Cas No: 681853-95-2

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681853-95-2 Usage

Description

(-)-1-[(4S,5S)-2,2-dimethyl-5-vinyl-1,3-dioxolan-4-yl]-2-(tert-butyldiphenylsilyloxy)ethan-1-one is a complex chemical compound that features a dioxolane ring and a silyl-protected hydroxy group. It possesses a stereocenter at the 4th and 5th positions, which gives it a unique spatial arrangement of its atoms. (-)-1-[(4S,5S)-2,2-dimethyl-5-vinyl-1,3-dioxolan-4-yl]-2-(tert-butyldiphenylsilyloxy)ethan-1-one also includes a vinyl group and a tert-butyldiphenylsilyloxy group, contributing to its chemical reactivity and properties. Its intricate structure and functional groups render it a valuable intermediate in organic synthesis, with promising applications in pharmaceutical and materials chemistry.

Uses

Used in Pharmaceutical Chemistry:
(-)-1-[(4S,5S)-2,2-dimethyl-5-vinyl-1,3-dioxolan-4-yl]-2-(tert-butyldiphenylsilyloxy)ethan-1-one serves as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and functional groups allow for the development of new drugs with specific therapeutic properties.
Used in Materials Chemistry:
In the field of materials chemistry, (-)-1-[(4S,5S)-2,2-dimethyl-5-vinyl-1,3-dioxolan-4-yl]-2-(tert-butyldiphenylsilyloxy)ethan-1-one is utilized for the creation of advanced materials with tailored properties. Its versatility in organic synthesis enables the production of materials with applications in various industries, such as electronics, coatings, and adhesives.
Used in Organic Synthesis:
As an intermediate in organic synthesis, (-)-1-[(4S,5S)-2,2-dimethyl-5-vinyl-1,3-dioxolan-4-yl]-2-(tert-butyldiphenylsilyloxy)ethan-1-one is employed in the preparation of complex organic molecules. Its presence in the synthesis process allows for the creation of compounds with specific functionalities and properties, which can be further utilized in various applications across different industries.

Check Digit Verification of cas no

The CAS Registry Mumber 681853-95-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,8,1,8,5 and 3 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 681853-95:
(8*6)+(7*8)+(6*1)+(5*8)+(4*5)+(3*3)+(2*9)+(1*5)=202
202 % 10 = 2
So 681853-95-2 is a valid CAS Registry Number.

681853-95-2Relevant articles and documents

POLYMORPHIC COMPOUNDS AND USES THEREOF

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, (2020/04/10)

The present invention provides compounds and methods of use thereof for treatment of certain disorders and conditions, for example brain injuries such as stroke or traumatic brain injuries.

Compounds and methods for treating neurological and cardiovascular conditions

-

, (2017/11/09)

The present invention relates to compounds and methods of use thereof for treatment of certain disorders and conditions, for example brain injuries such as stroke or traumatic brain injuries.

Synthesis, activity and metabolic stability of non-ribose containing inhibitors of histone methyltransferase DOT1L

Deng, Lisheng,Zhang, Li,Yao, Yuan,Wang, Cong,Redell, Michele S.,Dong, Shuo,Song, Yongcheng

, p. 822 - 826 (2013/08/26)

Histone methyltransferase DOT1L is a drug target for MLL leukemia. We report an efficient synthesis of a cyclopentane-containing compound that potently and selectively inhibits DOT1L (Ki = 1.1 nM) as well as H3K79 methylation (IC50 ~

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