6836-23-3

Basic information

• Product Name: (7-methoxy-1-naphthyl)acetic acid chloride
• Synonyms: (7-methoxy-1-naphthyl)acetic acid chloride
• CAS NO: 6836-23-3
• Molecular Weight: 234.682
• Mol File: 6836-23-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (7-methoxy-1-naphthyl)acetic acid chloride(CAS DataBase Reference)
• NIST Chemistry Reference: (7-methoxy-1-naphthyl)acetic acid chloride(6836-23-3)
• EPA Substance Registry System: (7-methoxy-1-naphthyl)acetic acid chloride(6836-23-3)

Safety Data

• Hazardous Substances Data: 6836-23-3(Hazardous Substances Data)

Upstream product

• 6836-20-0 ethyl (7-methoxy-1,2,3,4-tetrahydro-1-naphthalenylidene)acetate 
• 63319-95-9 [7-Methoxy-3,4-dihydro-2H-naphthalen-(1E)-ylidene]-acetic acid 
• 27532-26-9 ethyl (1,2,3,4-tetrahydro-7-methoxy-1-naphthyl)acetate 
• 6836-21-1 ethyl 2-(7-methoxynaphthalen-1-yl)acetate 
• 6836-19-7 7-Methoxy-1-tetralone 
• 6836-22-2 2-(7-methoxynaphthalen-1-yl)acetic acid 

Downstream Products

• 138113-09-4 2-(7-methoxynaphth-1-yl)ethylamine 
• 138112-95-5 S 20255 
• 138112-91-1 S 20254 
• 138113-02-7 S 20305 
• 138112-77-3 S 20099 
• 138113-13-0 N-[2-(7-methoxy-1-naphthyl)ethyl]cyclobutanecarboxamide 
• 138112-87-5 S 20253 
• 138112-80-8 S 20303 
• 138113-03-8 N-[2-(7-methoxy-1-naphthyl)ethyl]cyclopropanecarboxamide 
• 138112-99-9 N-[2-(7-Methoxynaphth-1-yl)Ethyl]-Butyramide 
• 138112-78-4 S 20100 
• 138112-79-5 N-[2-(7-methoxy-1-naphthyl)ethyl]propionamide 
• 138112-76-2 agomelatine 
• 139525-77-2 2-(7-methoxynaphthalen-1-yl)ethanamine hydrochloride 

Relevant articles and documents

PROCESS FOR PREPARATION OF AGOMELATINE AND CRYSTALLINE FORM I THEREOF

An improved process for the preparation of agomelatine of formula (I) and a new process for the preparation of crystalline form I of agomelatine are provided.

AGOMELATINE AND PHARMACEUTICAL COMPOSITIONS THEREOF

Agomelatine crystal, which is a drug for treating depression, and pharmaceutical compositions thereof are provided. The X-ray powder diffraction spectra of such agomelatine crystal, which is irradiated by Cu-Kα and showed by 20(degree), has characteristic diffraction peaks at 12.84, 13.84, 16.14, 18.56, 19.12, 20.86, 21.20, 23.84; its IR absorption pattern has characteristic absorption peaks at about 3234, 3060, 2940, 1638, 1511, 1436, 1249, 1215, 1184, 1032, 908, 828, 755, 588 cm-1; and its DSC endothermic transition temperature is 97.6°C. The use of the agomelatine crystal as an active ingredient in preparing a medicament for the treatment of depression is also provided.

Synthesis of the naphthalenic bioisostere of indorenate

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