68372-66-7

Basic information

• Product Name: 1β,5β,7α,-7-hydroxy-2-oxabicyclo<3.3.0>octan-3-one
• CAS NO: 68372-66-7
• Molecular Weight: 142.155
• Mol File: 68372-66-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1β,5β,7α,-7-hydroxy-2-oxabicyclo<3.3.0>octan-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1β,5β,7α,-7-hydroxy-2-oxabicyclo<3.3.0>octan-3-one(68372-66-7)
• EPA Substance Registry System: 1β,5β,7α,-7-hydroxy-2-oxabicyclo<3.3.0>octan-3-one(68372-66-7)

Safety Data

• Hazardous Substances Data: 68372-66-7(Hazardous Substances Data)

Upstream product

• 694-98-4 norborn-5-en-2-one 
• 56011-39-3 (1R*,2S*,3S*,5R*)-(±)-2-bromo-3-hydroxybicyclo[3.2.0]heptan-6-one 
• 13173-09-6 bicyclo[3.2.0]hept-2-en-6-one 
• 74877-19-3 cis-2-(4-hydroxycyclopent-2-enyl)acetic acid 
• 56460-52-7 1β,5β,7α,8β-7-hydroxy-8-iodo-2-oxabicyclo<3.3.0>octan-3-one 

Downstream Products

• 1357495-82-9 benzyl 2-(6-oxo-2,4,5,6-tetrahydrocyclopenta[c]pyrrol-4-yl)-acetate 
• 158604-58-1 benzyl 2-(4-oxocyclopent-2-en-1-yl)acetate 

Relevant articles and documents

Synthesis of 3,4-fused cycloalkanopyrroles by 1,3-dipolar cycloaddition

The synthesis of a number of 3,4-fused cycloalkanopyrroles bearing substituents on the cycloalkane ring was accomplished by 1,3-dipolar cycloaddition. The yield of the cyclization appeared to depend on the base-sensitivity of the Michael acceptor, but the method is applicable across a broad range of cyclic α,β-unsaturated ketone esters. Functional group transformations can be undertaken following pyrrole synthesis to increase the diversity of cycloalkanopyrroles accessible by this method. One pyrrole thus made is a diester of a conformationally-constrained analogue of porphobilinogen, the precursor of the natural tetrapyrroles.