6853-58-3

Basic information

• Product Name: 1-(broMoMethyl)-4-n-pentylbenzene
• Synonyms: 1-(broMoMethyl)-4-n-pentylbenzene
• CAS NO: 6853-58-3
• Molecular Formula: C₁₂H₁₇Br
• Molecular Weight: 241.16738
• Mol File: 6853-58-3.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(broMoMethyl)-4-n-pentylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(broMoMethyl)-4-n-pentylbenzene(6853-58-3)
• EPA Substance Registry System: 1-(broMoMethyl)-4-n-pentylbenzene(6853-58-3)

Safety Data

• Hazardous Substances Data: 6853-58-3(Hazardous Substances Data)

Upstream product

• 623-24-5 1,4-bis(bromomethyl)benzene 
• 693-04-9 butyl magnesium bromide 
• 26311-45-5 4-pentylbenzoic acid 
• 49763-65-7 4-pentylbenzoyl chloride 
• 6853-57-2 4-pentylbenzaldehyde 
• 81720-37-8 4-n-pentylbenzyl alcohol 

Downstream Products

• 1595-09-1 1-methyl-4-n-pentylbenzene 
• 83805-09-8 4-pentylbenzyl 4-propylphenyl ketone 
• 60982-71-0 (4-n-pentylphenyl)acetonitrile 
• 94721-65-0 p-(p-pentylphenylmethoxy)benzoic acid 
• 950508-69-7 2-(4-n-pentylphenyl)-3-phenylpropan-2-one 
• 94721-75-2 4-(4-Pentyl-benzyloxy)-benzoic acid 4-cyano-phenyl ester 
• 94721-74-1 4-(4-Pentyl-benzyloxy)-benzoic acid 4-pentyl-phenyl ester 
• 14377-21-0 4-pentylphenylethanoic acid 
• 1259085-81-8 2-((4-pentylbenzyl)oxy)isoindoline-1,3-dione 
• 1427308-28-8 tert-butyl 2,2-dimethyl-5-(4-(4-pentylbenzyl)phenethyl)-1,3-dioxan-5-ylcarbamate 

Relevant articles and documents

Azole-based non-peptidomimetic plasmepsin inhibitors

The spread of drug-resistant malaria parasites urges the search for new antimalarial drugs. Malarial aspartic proteases – plasmepsins (Plms) – are differentially expressed in multiple stages of the Plasmodium parasite's lifecycle and are considered as attractive drug targets. We report the development of novel azole-based non-peptidomimetic plasmepsin inhibitors that have been designed by bioisosteric substitution of the amide moiety in the Actelion amino-piperazine inhibitors. The best triazole-based inhibitors show submicromolar potency toward Plm II, which is comparable to that of the parent Actelion compounds. The new inhibitors can be used as a starting point for the development of a resistance-free antimalarial drug targeting the non-digestive Plm IX or X, which are essential for the malaria parasite life cycle.

Odorless substitutes for foul-smelling thiols: Syntheses and applications

Several alkanethiols and p-alkylphenylmethanethiols were synthesized, and their odors were compared with those of ethanethiol and benzyl mercaptan by human and instrumental sensors. Among the various thiols analyzed, 1-dodecanethiol (1) and p-heptylphenylmethanethiol (3) were revealed to be odorless. 1-Dodecanethiol (1) has been used instead of ethanethiol for dealkylation of ethers, and p-heptylphenylmethanethiol (3) can replace benzyl mercaptan in the preparation of a 1,3-mercapto alcohol from an α,β-unsaturated ketone. These odorless thiols will greatly improve the physical environment of the researcher working with these foul-smelling compounds.

Phenacenes: A family of graphite ribbons. 1. Syntheses of some [7]phenacenes by stilbene-like photocyclizations

The largest previously reported phenacene, the name we propose for the family of polycyclic aromatic compounds having fused benzene rings in an extended phenanthrene-like structural motif, contains only six rings ([6]phenacene). We have employed stilbene-like photocyclizations to synthesize the unsubstituted [7]phenacene, an extremely insoluble compound, as well as 2,13-di-n-pentyl[7]phenacene and 2,13-di-tert-butyl[7]phenacene, two alkyl-substituted derivatives with greatly improved solubilities.