68935-27-3

Basic information

• Product Name: (+)-NICOTINE (+)-DI-P-TOLUOYLTARTRATE SALT
• Synonyms: R(+)-3-(1-METHYL-2-PYRROLIDINYL)PYRIDINIUM (+)-DI-P-TOLUOYL TARTRATE;(+)-NICOTINE DI-P-TOLUOYL-D-TARTRATE SALT;(+)-NICOTINE (+)-DI-P-TOLUOYLTARTRATE SALT;(+)-nicotine (+)-di-P-toluoyltartrate;Di-p-Toluoyl-D-tartratesalt;S(-)-3-(1-Methyl-2-pyrrolidinyl)pyridinium (+)-di-p-toluoyl tartrate;(+)-Di-p-toluoyltartrate salt;(S)-3-(1-Methyl-2-pyrrolidinyl-pryidine (R-(R,R))-2,3-dihydroxybutanedioate
• CAS NO: 68935-27-3
• Molecular Formula: C₁₀H₁₄N₂*C₂₀H₁₈O₈
• Molecular Weight: 548.58
• Product Categories: Chiral Reagents;Nicotine Derivatives;Aromatics;Heterocycles;Mutagenesis Research Chemicals
• Mol File: 68935-27-3.mol
• Article Data: 1

Chemical Properties

• Melting Point: 148-149°C dec.
• Appearance: white to off-white/powder
• Storage Temp.: 2-8°C
• Solubility: H2O: soluble
• CAS DataBase Reference: (+)-NICOTINE (+)-DI-P-TOLUOYLTARTRATE SALT(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-NICOTINE (+)-DI-P-TOLUOYLTARTRATE SALT(68935-27-3)
• EPA Substance Registry System: (+)-NICOTINE (+)-DI-P-TOLUOYLTARTRATE SALT(68935-27-3)

Safety Data

• Hazard Codes: T
• Statements: 23/24/25-36/37/38-40
• Safety Statements: 22-36-45
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• Hazardous Substances Data: 68935-27-3(Hazardous Substances Data)

Usage

Description

(+)-Nicotine (+)-Di-p-toluoyl-D-tartrate salt is a chemical compound that serves as a precursor to the less active enantiomer of naturally occurring (-)-nicotine. It is characterized by its potent neurotoxic properties.

Uses

Used in Pharmaceutical Industry:
(+)-Nicotine (+)-Di-p-toluoyl-D-tartrate salt is used as a precursor in the synthesis of (-)-nicotine, which is an important compound in the development of medications targeting the nervous system. Its potent neurotoxin nature makes it a valuable research tool for understanding the mechanisms of nicotine addiction and potential therapeutic applications.
Used in Research and Development:
(+)-Nicotine (+)-Di-p-toluoyl-D-tartrate salt is utilized in research settings to study the effects of nicotine and its analogs on the central nervous system. This helps scientists to develop a better understanding of nicotine's impact on brain function and to explore potential treatments for nicotine addiction and related disorders.

Upstream product

• 25162-00-9 D-nicotine 
• 32634-68-7 (2S,3S)-di-4-toluoyltartaric acid 
• 22083-74-5 3-(1-methyl-pyrrolidin-2-yl)-pyridine 

Relevant articles and documents

A process for the resolution of (R,S)-nicotine

(R,S)-Nicotine was resolved through diastereomeric salt formation using dibenzoyl-d-tartaric acid and dibenzoyl-l-tartaric acid to obtain enantiomerically pure (S)-nicotine and (R)-nicotine.