690264-82-5

Basic information

• Product Name: [1-(5-bromo-pyridin-2-yl)-pyrrolidin-3-yl]-dimethyl-amine
• Synonyms: [1-(5-bromo-pyridin-2-yl)-pyrrolidin-3-yl]-dimethyl-amine;1-(5-BroMopyridin-2-yl)-N,N-diMethylpyrrolidin-3-aMine;1-(5-bromo-2-pyridinyl)-N,N-dimethyl-3-pyrrolidinamine
• CAS NO: 690264-82-5
• Molecular Formula: C₁₁H₁₆BrN₃
• Molecular Weight: 270
• Mol File: 690264-82-5.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: [1-(5-bromo-pyridin-2-yl)-pyrrolidin-3-yl]-dimethyl-amine(CAS DataBase Reference)
• NIST Chemistry Reference: [1-(5-bromo-pyridin-2-yl)-pyrrolidin-3-yl]-dimethyl-amine(690264-82-5)
• EPA Substance Registry System: [1-(5-bromo-pyridin-2-yl)-pyrrolidin-3-yl]-dimethyl-amine(690264-82-5)

Safety Data

• Hazardous Substances Data: 690264-82-5(Hazardous Substances Data)

Usage

General Description

"[1-(5-bromo-pyridin-2-yl)-pyrrolidin-3-yl]-dimethyl-amine is a chemical compound with the molecular formula C11H16BrN3. It is a pyrrolidine derivative that contains a pyrrolidin-3-yl group attached to a dimethylamine moiety, as well as a bromo-pyridin-2-yl group. [1-(5-bromo-pyridin-2-yl)-pyrrolidin-3-yl]-dimethyl-amine has potential applications in the pharmaceutical and chemical industries, particularly in drug discovery and development. It may be utilized as a building block in organic synthesis, and its unique structural features could make it a valuable starting material for the creation of novel bioactive molecules. Further research is needed to fully understand the potential uses and properties of this chemical."

Upstream product

• 1160938-10-2 1-(5-bromo-2-pyridinyl)-3-pyrrolidinyl methanesulfonate 
• 124-40-3 dimethyl amine 
• 106-37-6 1.4-dibromobenzene 
• 69478-75-7 dimethyl-pyrrolidin-3-yl-amine 
• 624-28-2 2,5-dibromopyridine 

Downstream Products

• 959960-54-4 6'-[3-(dimethylamino)-1-pyrrolidinyl]-4-[(phenylmethyl)oxy]-2H-1,3'-bipyridin-2-one 
• 868662-07-1 1-(2,4-dimethoxy-phenyl)-2-[6-(3-dimethylamino-pyrrolidin-1-yl)-pyridin-3-yl]-ethanone 
• 868662-32-2 1-(4-benzyloxy-2-fluoro-phenyl)-2-[6-(3-dimethylamino-pyrrolidin-1-yl)-pyridin-3-yl]-ethanone 

Relevant articles and documents

BIS-PYRIDYLPYRIDONES AS MELANIN-CONCENTRATING HORMONE RECEPTOR 1 ANTAGONISTS

The invention provides novel bis-pyridylpyridones which are antagonists at the melanin-concentrating hormone receptor 1 (MCHR1), pharmaceutical compositions containing them, processes for their preparation, and their use in therapy and for the treatment of obesity and/or diabetes.

Substituted chromones and quinolones as potent melanin-concentrating hormone receptor 1 antagonists

A series of substituted chromones were designed, synthesized, and evaluated for their ability to bind melanin-concentrating hormone receptor 1. Compounds with subnanomolar binding affinity and 66% oral bioavailability in rats were discovered.

Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds

The present invention relates to alkyne compounds of general formula I wherein the groups and residues A, B, W, X, Y, Z, R1 and R2 have the meanings given in claim 1. The invention further relates to pharmaceutical compositions containing at least one alkyne according to the invention. In view of their MCH-receptor antagonistic activity the pharmaceutical compositions according to the invention are suitable for the treatment of metabolic disorders and/or eating disorders, particularly obesity, bulimia, anorexia, hyperphagia and diabetes.