6908-73-2Relevant articles and documents
B(C6F5)3-catalyzed tandem protonation/deuteration and reduction of: In situ -formed enamines
Wu, Rongpei,Gao, Ke
supporting information, p. 4032 - 4036 (2021/05/19)
A highly efficient B(C6F5)3-catalyzed tandem protonation/deuteration and reduction of in situ-formed enamines in the presence of water and pinacolborane was developed. Regioselective β-deuteration of tertiary amines was achieved with high chemo- and regioselectivity. D2O was used as a readily available and cheap source of deuterium. Mechanistic studies indicated that B(C6F5)3 could activate water to promote the protonation and reduction of enamines. This journal is
Revisiting the role of acids and hydrogen bond acceptors in enamine formation
Hammond, Gerald B.,Lu, Zhichao,Xu, Bo
supporting information, p. 6849 - 6852 (2020/10/02)
A systematic investigation into the effects of acids and hydrogen bond acceptors on the reaction rates and equilibria of enamine formation is reported. Acids can accelerate the reaction but do not change the reaction equilibria. In comparison, hydrogen bond acceptors facilitate the enamine formation via their strong hydrogen bonding interaction with the water generated in the reaction.
METHOD FOR PRODUCING FLUORINE-CONTAINING COMPOUND
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Paragraph 0101-0104; 0110-0112, (2019/10/15)
PROBLEM TO BE SOLVED: To provide a method for producing a fluorine-containing compound by the addition reaction of an olefin to a perfluoroalkyl radical, which can be performed industrially in a more suitable manner. SOLUTION: A method for producing a flu