70090-69-6

Basic information

• Product Name: 1-Chloro-4-prop-2-ynyl-benzene
• Synonyms: 1-Chloro-4-prop-2-ynyl-benzene
• CAS NO: 70090-69-6
• Molecular Formula: C₉H₇Cl
• Molecular Weight: 150.60488
• Mol File: 70090-69-6.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Chloro-4-prop-2-ynyl-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Chloro-4-prop-2-ynyl-benzene(70090-69-6)
• EPA Substance Registry System: 1-Chloro-4-prop-2-ynyl-benzene(70090-69-6)

Safety Data

• Hazardous Substances Data: 70090-69-6(Hazardous Substances Data)

Usage

Physical state

Colorless liquid.

Odor

Pungent.

Usage

Building block for the synthesis of various organic compounds.

Primary applications

Production of pharmaceuticals, pesticides, and dyes.

Industrial uses

Manufacturing of polymers and resins.

Safety precautions

Harmful if inhaled, ingested, or comes into contact with the skin.

Storage conditions

Cool, dry place away from heat and direct sunlight.

Upstream product

• 13169-00-1 Methoxyallene 
• 873-77-8 (4-chlorphenyl)magnesium bromide 
• 622-95-7 4-chlorobenzyl bromide 
• 104-88-1 4-chlorobenzaldehyde 
• 4251-65-4 (4-chlorophenyl)acetaldehyde 
• 106-96-7 propargyl bromide 
• 29805-11-6 1-(4-chlorophenyl)prop-2-yn-1-ol 
• 104-83-6 1-Chloro-4-(chloromethyl)benzene 
• 4301-14-8 acetylenemagnesium bromide 

Downstream Products

• 74444-81-8 5-chloro-1,3-dihydro-2H-inden-2-one 
• 199679-74-8 (R)-2-methyl-3-(4-chlorophenyl)propionic acid 
• 1450831-14-7 1-chloro-4-(4,4,4-trifluorobut-1-yn-1-yl)benzene 
• 2809-65-6 4-chloro-1-propynylbenzene 
• 2749-98-6 4-chlorophenylallene 
• 1443207-44-0 ethyl 2-(4-chlorobenzyl)-1-(trifluoromethyl)cycloprop-2-enecarboxylate 
• 70041-47-3 (E)-3-(4-chlorobenzylidene)-5-phenylfuran-2(3H)-one 
• 742067-49-8 6-(4-chloro-benzyl)-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile 
• 98011-78-0 (Z)-4-(4-chlorophenyl)-N,N-diethyl-N-heptyl-2-butenaminium 4-methylbenzenesulfonate 
• 98011-69-9 (Z)-4-(4-chlorophenyl)-2-buten-1-ol 4-methylbenzenesulfonate 
• 98011-68-8 (Z)-4-(4-chlorophenyl)but-2-en-1-ol 
• 34905-12-9 4-(4-chlorophenyl)-2-butyn-1-ol 

Relevant articles and documents

Ruthenium-Catalyzed Propargylic Reduction of Propargylic Alcohols with Hantzsch Ester

Ruthenium-catalyzed propargylic reduction of propargylic alcohols bearing a terminal alkyne moiety is accomplished by using Hantzsch ester as a nucleophilic hydride source. A variety of secondary and tertiary propargylic alcohols are reduced to the corresponding propargylic reduced products such as 1-alkynes in excellent yields. Some mechanistic studies indicate that ruthenium-allenylidene complexes may work as key reactive intermediates.

Removal of human ether-à-go-go related gene (hERG) K+ channel affinity through rigidity: A case of clofilium analogues

Cardiotoxicity is a side effect that plagues modern drug design and is very often due to the off-target blockade of the human ether-à-go-go related gene (hERG) potassium channel. To better understand the structural determinants of this blockade, we design

An efficient synthesis of isotope-labeled PD0331179 and its labeled metabolite

4-[1-Methyl-2,4-dioxo-6-(3-phenyl-prop-1-ynyl)-1,4-dihydro-2H-quinazolin-3- ylmethyl]-benzoic acid, PD0331179, was under investigation as a matrix metalloproteinase-13 inhibitor. 14C-labeled and 2H-labeled PD0331179 and its 2/s