70290-37-8

Basic information

• Product Name: 2-(4-(Methylthio)phenyl)acetic acid
• Synonyms: methyl 2-(4-(methylthio)phenyl)acetate;(4-METHYLSULFANYLPHENYL)ACETIC ACID METHYL ESTER
• CAS NO: 70290-37-8
• Molecular Formula: C₁₀H₁₂O₂S
• Molecular Weight: 182.2395
• Mol File: 70290-37-8.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 179-181 °C(Press: 3 Torr)
• Appearance: /
• Density: 1.13±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 2-(4-(Methylthio)phenyl)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-(Methylthio)phenyl)acetic acid(70290-37-8)
• EPA Substance Registry System: 2-(4-(Methylthio)phenyl)acetic acid(70290-37-8)

Safety Data

• Hazardous Substances Data: 70290-37-8(Hazardous Substances Data)

Upstream product

• 1197-55-3 4-aminophenylacetic acid 
• 39161-84-7 4-mercaptophenylacetic acid 
• 1235544-51-0 2-(4-((ethoxycarbonothioyl)thio)phenyl)acetic acid 
• 186581-53-3 diazomethane 
• 16188-55-9 2-(4-(methylthio)phenyl)acetic acid 
• 74-88-4 methyl iodide 
• 1798-06-7 (4-iodophenyl)acetic acid 
• 67-56-1 methanol 

Downstream Products

• 118362-12-2 S-Methyl-S-(4-methoxycarbonylmethyl-phenyl)-N-p-tolylsulfonyl-sulfilimin 
• 118362-27-9 (4-Methanesulfinyl-phenyl)-acetic acid methyl ester 
• 81227-89-6 2-[4-(methylmercapto)phenyl]-1-ethanol 
• 300355-18-4 (4-methanesulfonyl-phenyl)-acetic acid methyl ester 
• 557798-35-3 bromo-(4-methylsulfonyl-phenyl)-acetic acid methyl ester 
• 454185-98-9 methyl [4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetate 
• 1283595-72-1 C₂₁H₃₀O₄S 
• 1283595-70-9 (R)-2-[4-(methylsulfonyl)phenyl]-3-((R)-3-oxocyclopentyl)propanoic acid 
• 1283595-69-6 (S)-2-[4-(methylsulfonyl)phenyl]-3-((R)-3-oxocyclopentyl)propanoic acid 
• 1361094-39-4 C₂₀H₂₈O₆S 
• 1283595-74-3 C₂₀H₂₈O₆S 
• 1283595-73-2 C₂₀H₂₈O₄S 
• 300355-67-3 (3-bromo-4-methylsulfanylphenyl)acetic acid methyl ester 
• 691881-05-7 1-[3-cyclohexyl-5-hydroxy-1-(2-hydroxyethyl)-pyrazol-4-yl]-4-(methylsulfonyl)benzene 

Relevant articles and documents

Rhodium-Catalyzed ipso-Borylation of Alkylthioarenes via C-S Bond Cleavage

Rhodium-catalyzed transformation of alkyl aryl sulfides into arylboronic acid pinacol esters via C-S bond cleavage is reported. In combination with transition-metal-catalyzed sulfanyl group-guided regioselective C-H borylation reactions of alkylthioarenes, this method allows the synthesis of a diverse range of multisubstituted arenes.

TRISUBSTITUTED HETEROCYCLIC DERIVATIVES AS ROR GAMMA MODULATORS

The present invention provides trisubstituted heterocyclic derivatives of formula (I), which may be therapeutically useful, more particularly as RORγ modulators; (I) in which R1, R2, R3, Ra, X, L, m and ring A have the meanings given in the specification, and pharmaceutically acceptable salts thereof that are useful in the treatment and prevention of diseases or disorder, in particular their use in diseases or disorder where there is an advantage in modulating RORγ receptor. The present invention also provides preparation of the compounds and pharmaceutical formulations comprising at least one of the trisubstituted heterocyclic derivatives of formula (I) together with a pharmaceutically acceptable carrier, diluent or excipient therefor.

5-(4-methanesulfonyl-phenyl)-thiazole derivatives for the treatment of acute and chronic inflammatory diseases

The invention relates to the use of a compound of formula (I): or a pharmaceutically acceptable salt, prodrug and/or solvate thereof, in the preparation of a medicament for the treatment of an acute or chronic inflammatory disease, by inhibiting the produ