7071-83-2

Basic information

• Product Name: 9-FLUORENONE-4-CARBONYL CHLORIDE
• Synonyms: 9-OXO-4-FLUORENECARBONYL CHLORIDE;9-FLUORENONE-4-CARBONYL CHLORIDE;TIMTEC-BB SBB000824;9-Oxo-9H-fluorene-4-carbonyl chloride;9H-FLUORENE-4-CARBONYL CHLORIDE,9-OXO
• CAS NO: 7071-83-2
• Molecular Formula: C₁₄H₇ClO₂
• Molecular Weight: 242.66
• Mol File: 7071-83-2.mol
• Article Data: 5

Chemical Properties

• Melting Point: 139-141 °C(lit.)
• Boiling Point: 420.1°C at 760 mmHg
• Flash Point: 177.4°C
• Appearance: /
• Density: 1.417g/cm³
• Vapor Pressure: 2.89E-07mmHg at 25°C
• Refractive Index: 1.672
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 9-FLUORENONE-4-CARBONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 9-FLUORENONE-4-CARBONYL CHLORIDE(7071-83-2)
• EPA Substance Registry System: 9-FLUORENONE-4-CARBONYL CHLORIDE(7071-83-2)

Safety Data

• Hazard Codes: C
• Statements: 34-40
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3261 8/PG 2
• WGK Germany: 1
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 7071-83-2(Hazardous Substances Data)

Usage

Description

9-Fluorenone-4-carbonyl chloride is a fluorescent electrophilic reagent, characterized by its ability to react with various substrates due to its electrophilic nature and its fluorescence property, which can be useful for tracking and analyzing reactions.

Uses

Used in Chemical Synthesis:
9-Fluorenone-4-carbonyl chloride is used as a reagent for the functionalization of amino acids in alkaline medium before their enantioresolution by HPLC. This application takes advantage of its electrophilic properties to modify amino acids, which can then be separated based on their chirality.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 9-Fluorenone-4-carbonyl chloride is used as a synthetic intermediate for the synthesis of N-(2-hydroxyethyl)-9-oxo-9H-fluorene-4 carboxamide. 9-FLUORENONE-4-CARBONYL CHLORIDE has potential applications in the development of new drugs, leveraging the reagent's electrophilic and fluorescent characteristics to create novel molecular structures with potential therapeutic properties.
Used in Research and Development:
9-Fluorenone-4-carbonyl chloride's fluorescence property makes it a valuable tool in research and development, particularly in the fields of biochemistry and molecular biology. It can be used to label and track specific molecules or biological processes, aiding in the understanding of complex biochemical pathways and the development of targeted therapies.

InChI:InChI=1/C14H7ClO2/c15-14(17)11-7-3-6-10-12(11)8-4-1-2-5-9(8)13(10)16/h1-7H

Upstream product

• 863305-32-2 diphenic acid 
• 6223-83-2 9-oxo-9H-fluorene-4-carboxylic acid 
• 120-95-6 2,4-di-tert-amylphenol 
• 71-43-2 benzene 
• 6050-13-1 biphenyl-2,2'-dicarboxylic acid anhydride 

Downstream Products

• 883-33-0 4-iodo-9H-fluoren-9-one 
• 1021018-74-5 9-oxo-9H-fluoren-4-carboxylic acid (2-hydroxy-phenyl)-amide 
• 1094495-38-1 C₄₉H₆₀N₄O₂₂ 
• 915141-84-3 9-oxo-9H-fluorene-4-carboxylic acid (2-amino-4-bromophenyl)amide 
• 915140-22-6 C₂₁H₁₆N₂O₃ 
• 915140-23-7 9-oxo-9H-fluorene-4-carboxylic acid (2-amino-4-methoxyphenyl)amide 
• 915141-49-0 9-oxo-9H-fluorene-4-carboxylic acid (2-amino-4-sulphamoylphenyl)amide 
• 915141-79-6 9-oxo-9H-fluorene-4-carboxylic acid (2-amino-4-chlorophenyl)amide 
• 500360-94-1 [9,9-bis-(4-methoxy-3-methyl-phenyl)-fluoren-4-yl]-(4-methoxy-3-methyl-phenyl)-ketone 
• 214851-72-6 4-benzoyl-9H-fluoren-9-one 
• 4269-20-9 4-cyano-9-fluorenone 
• 6223-83-2 9-oxo-9H-fluorene-4-carboxylic acid 
• 7315-92-6 9,9-bis-phenylsulfanyl-fluorene-4-carbothioic acid S-phenyl ester 
• 4269-14-1 4-phenyl-9H-fluoren-9-one 

Relevant articles and documents

ELECTRON TRANSPORT MATERIAL, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS

Provided is an electron transport material represented by formula (1): wherein X represents an oxygen atom or ═C(CN)2; R1, R2, R3, R4, R5, R6, and R7 each independently represent a hydrogen atom, a halogen atom, a linear or branched alkyl group, an alkoxy group, an aryl group, or an aralkyl group; R8, R9, and R10 each independently represent a hydrogen atom, a halogen atom, a linear or branched alkyl group, an aralkyl group, an aryl group, —R11—O—R12, or —R13—CO—O—R14; R11 represents a linear or branched alkylene group; R12 represents a linear or branched alkyl group; R13 represents a single bond or a linear or branched alkylene group; and R14 represents a linear or branched alkyl group, an aryl group, or an aralkyl group, provided that at least two or more groups of R8, R9, and R10 represent a group other than a hydrogen atom.

Use of structure-based drug design approaches to obtain novel anthranilic acid acyl carrier protein synthase inhibitors

Acyl carrier protein synthase (AcpS) catalyzes the transfer of the 4′-phosphopantetheinyl group from the coenzyme A to a serine residue in acyl carrier protein (ACP), thereby activating ACP, an important step in cell wall biosynthesis. The structure-based

Synthesis and monolayer spreading behaviour of surface-active compounds containing electron- and hole-transporting groups. 1. Fluorenylidene derivatives

Surface-active derivatives containing fluorenylidene groups were synthesized, with the goal of creating thin-film devices incorporating monolayers of electron-transporting materials.The new compounds were studied in monolayers at the air-water interface, and were further characterized by cyclic voltammetry.The spreading behaviour of long-chain esters of a fluorenylidene malononitrile carboxylic acid was relatively insensitive to the cross-sectional area of the hydrocarbon chain, but was more strongly affected by changes in the polarity of the hydrophilic groups.Conditions for Langmuir-Blodgett deposition of multilayers of two of the new compounds on titanium-coated polyester film were also explored.Key words: monolayers, Langmuir-Blodgett films, fluorene, surfactants