70730-22-2

Basic information

• Product Name: 4-(2,5-dioxopyrrolidin-1-yl)benzonitrile
• Synonyms: 4-(2,5-dioxopyrrolidin-1-yl)benzonitrile
• CAS NO: 70730-22-2
• Molecular Weight: 200.197
• Mol File: 70730-22-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(2,5-dioxopyrrolidin-1-yl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2,5-dioxopyrrolidin-1-yl)benzonitrile(70730-22-2)
• EPA Substance Registry System: 4-(2,5-dioxopyrrolidin-1-yl)benzonitrile(70730-22-2)

Safety Data

• Hazardous Substances Data: 70730-22-2(Hazardous Substances Data)

Upstream product

• 303213-70-9 4-[(4-cyanophenyl)amino]-4-oxobutanoic acid 
• 108-24-7 acetic anhydride 
• 123-56-8 Succinimide 
• 126747-14-6 4-cyanophenylboronic acid 
• 873-74-5 4-Aminobenzonitrile 
• 31489-18-6 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzonitrile 

Relevant articles and documents

Reduction of Activated Alkenes by PIII/PV Redox Cycling Catalysis

The carbon–carbon double bond of unsaturated carbonyl compounds was readily reduced by using a phosphetane oxide catalyst in the presence of a simple organosilane as the terminal reductant and water as the hydrogen source. Quantitative hydrogenation was observed when 1.0 mol % of a methyl-substituted phosphetane oxide was employed as the catalyst. The procedure is highly selective towards activated double bonds, tolerating a variety of functional groups that are usually prone to reduction. In total, 25 alkenes and two alkynes were hydrogenated to the corresponding alkanes in excellent yields of up to 99 %. Notably, less active poly(methylhydrosiloxane) could also be utilized as the terminal reductant. Mechanistic investigations revealed the phosphane as the catalyst resting state and a protonation/deprotonation sequence as the crucial step in the catalytic cycle.