70855-14-0Relevant articles and documents
Ligand Control of Palladium-Catalyzed Site-Selective α- and γ-Arylation of α,β-Unsaturated Ketones with (Hetero)aryl Halides
So, Chau Ming,Yuen, On Ying
supporting information, p. 23438 - 23444 (2020/11/30)
This study describes the first palladium-catalyzed, site-selective α- and γ-arylation of α,β-unsaturated ketones with (hetero)aryl halides. A wide range of hetero(aryl)halides coupled with α,β-unsaturated ketones, and transformation into the arylated products proceeded with excellent to good yields. The site selectivity of the reaction is switchable by simply changing the phosphine ligand to access either α-arylated or γ-arylated products in good to excellent yields by using a low catalyst loading, and the method demonstrates good functional-group compatibility.
One-pot synthesis of γ-diketones, γ-keto esters, and conjugated cyclopentenones from nitroalkanes
Ballini, Roberto,Barboni, Luciano,Bosica, Giovanna,Fiorini, Dennis
, p. 2725 - 2728 (2007/10/03)
Conjugated addition of primary nitroalkanes to α,β-unsaturated ketones or α,β-unsaturated esters, in the presence of two equivalents of DBU, allows the one-pot prepration of γ-diketones or γ-keto esters, respectively. When 2-aryl-1-nitroethane derivatives
AN IMPROVED, SIMPLE SYNTHESIS OF 3-METHYL-2-(4-METHYLPHENYL) CYCLOPENTEN-2-ONE: AN IMPORTANT INTERMEDIATE IN CUPARENE SYNTHESIS
Ballini, Roberto,Petrini, Marino,Marotta, Emanuela
, p. 543 - 548 (2007/10/02)
Conjugate addition of phenyl-1-methyl-4-(2-nitroethyl) to methyl vinyl ketone in presence of basic alumina, following by Nef reaction and basic cyclization, affords 3-methyl-2-(4-methyl phenyl) cyclopenten-2-one in good yield.
