71301-82-1Relevant articles and documents
An efficient synthesis of enantiomerically pure unnatural aryl glycinols and aryl glycines
Ku, Hui-Young,Jung, Junyang,Kim, Soo-Hyun,Kim, Hee Yeon,Ahn, Kyo Han,Kim, Sung-Gon
, p. 1111 - 1115 (2007/10/03)
A quick route to enantiomerically pure unnatural aryl glycinols and aryl glycines has been established based on an asymmetric azidation reaction using a chiral benzosultam auxiliary. The synthesis of aryl glycinols involves three steps starting from aryla
Nonproteinogenic Amino Acids, IV. - EPC Synthesis of L-(+)-Forphenicine
Weinges, Klaus,Reinel, Ute,Maurer, Wolfgang,Gaessler, Norbert
, p. 833 - 838 (2007/10/02)
Enantiomerically pure L-(+)-forphenicine (12) is synthesized starting from purchasable 3-methoxybenzaldehyde (1) by the use of (4S,5S)-(+)-5-amino-2,2-dimethyl-4-phenyl-1,3-dioxane (2) as a chiral auxiliary and prussic acid. 12 is identical with the natural product which has been isolated from the culture broth of an Actinomyces species and which is known to be a potent inhibitor of alkaline phosphatase.