71522-58-2

Basic information

• Product Name: forphenicinol
• Synonyms: forphenicinol;α-Amino-3-hydroxy-4-(hydroxymethyl)benzeneacetic acid
• CAS NO: 71522-58-2
• Molecular Formula: C₉H₁₁NO₄
• Molecular Weight: 197.189
• Mol File: 71522-58-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 334.28°C (rough estimate)
• Flash Point: 208.2°C
• Appearance: /
• Density: 1.3075 (rough estimate)
• Vapor Pressure: 7.96E-08mmHg at 25°C
• Refractive Index: 1.5270 (estimate)
• CAS DataBase Reference: forphenicinol(CAS DataBase Reference)
• NIST Chemistry Reference: forphenicinol(71522-58-2)
• EPA Substance Registry System: forphenicinol(71522-58-2)

Safety Data

• Hazardous Substances Data: 71522-58-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H11NO4/c10-8(9(13)14)5-1-2-6(4-11)7(12)3-5/h1-3,8,11-12H,4,10H2,(H,13,14)/t8-/m0/s1

Upstream product

• 108594-41-8 (2S)-(+)-2-<(1S,2S)-(2-Hydroxy-1-hydroxymethyl-2-phenylethyl)amino>-2-(3-methoxyphenyl)essigsaeure 
• 46988-94-7 (2S)-(+)-N-tert-Butoxycarbonyl-2-(3-hdroxyphenyl)glycin 
• 108647-55-8 (2S)-(+)-2-(3-Methoxyphenyl)glycin 
• 71301-82-1 (S)-3-hydroxyphenylglycine 
• 73036-70-1 (2S)-(+)-N-tert-Butoxycarbonyl-2-(3-hydroxy-4-hydroxymethylphenyl)glycin 

Downstream Products

• 636-94-2 2-hydroxyterephthalic acid 
• 74020-82-9 3-hydroxy-4-hydroxymethylbenzoic acid 
• 103521-30-8 3-hydroxy-4-hydroxymethylbenzylamine 
• 103521-31-9 α-(3-hydroxy-4-hydroxymethylphenyl)-α-oxoacetic acid 
• 103616-85-9 L-N-acetyl(3-hydroxy-4-hydroxymethylphenyl)glycine 

Relevant articles and documents

Nonproteinogenic Amino Acids, IV. - EPC Synthesis of L-(+)-Forphenicine

Enantiomerically pure L-(+)-forphenicine (12) is synthesized starting from purchasable 3-methoxybenzaldehyde (1) by the use of (4S,5S)-(+)-5-amino-2,2-dimethyl-4-phenyl-1,3-dioxane (2) as a chiral auxiliary and prussic acid. 12 is identical with the natural product which has been isolated from the culture broth of an Actinomyces species and which is known to be a potent inhibitor of alkaline phosphatase.