714269-57-5 Usage
Description
(2S,3R,4S,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxyMethyl)-2-Methoxytetrahydro-2H-pyran-3,4,5-triol is a complex organic compound with a unique molecular structure. It is characterized by its stereochemistry, with five chiral centers (2S, 3R, 4S, 5S, 6R), and a hydroxyMethyl group. (2S,3R,4S,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxyMethyl)-2-Methoxytetrahydro-2H-pyran-3,4,5-triol also features a 4-chloro-3-(4-ethoxybenzyl)phenyl group and a 2-methoxytetrahydro-2H-pyran-3,4,5-triol moiety. Its specific arrangement of functional groups and stereochemistry may contribute to its potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
(2S,3R,4S,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxyMethyl)-2-Methoxytetrahydro-2H-pyran-3,4,5-triol is used as an intermediate for the synthesis of various pharmaceutical compounds. Its unique structure and functional groups make it a valuable building block for the development of new drugs with potential therapeutic applications.
Used in Chemical Research:
In the field of chemical research, this compound can be used as a starting material for the synthesis of more complex molecules with specific properties. Its chiral centers and functional groups can be exploited to create novel compounds with potential applications in various industries, such as materials science, agrochemicals, and environmental science.
Used in Material Science:
(2S,3R,4S,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxyMethyl)-2-Methoxytetrahydro-2H-pyran-3,4,5-triol may be utilized in the development of new materials with specific properties, such as improved mechanical strength, thermal stability, or chemical resistance. Its unique molecular structure could contribute to the creation of advanced materials for various applications, including aerospace, automotive, and electronics industries.
Used in Agrochemical Industry:
(2S,3R,4S,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxyMethyl)-2-Methoxytetrahydro-2H-pyran-3,4,5-triol could potentially be used in the agrochemical industry as a starting material for the synthesis of new pesticides, herbicides, or fertilizers. Its specific functional groups and stereochemistry may allow for the development of more effective and targeted agrochemicals with reduced environmental impact.
Used in Environmental Science:
(2S,3R,4S,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxyMethyl)-2-Methoxytetrahydro-2H-pyran-3,4,5-triol may also find applications in environmental science, particularly in the development of new methods for pollution control, waste management, or environmental remediation. Its unique properties could be harnessed to create innovative solutions for addressing environmental challenges.
Check Digit Verification of cas no
The CAS Registry Mumber 714269-57-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,1,4,2,6 and 9 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 714269-57:
(8*7)+(7*1)+(6*4)+(5*2)+(4*6)+(3*9)+(2*5)+(1*7)=165
165 % 10 = 5
So 714269-57-5 is a valid CAS Registry Number.
714269-57-5Relevant articles and documents
AN EFFICIENT PROCESS FOR THE PREPARATION OF ERTUGLIFLOZIN L-PYROGLUTAMIC ACID AND INTERMEDIATES THEREOF
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Page/Page column 4; 13-14; 18, (2021/07/10)
The present invention relates to an efficient process for the preparation of Ertugliflozin L-pyroglutamic acid of formula (I) and intermediate thereof, in environment friendly conditions. The present invention further relates to a process for the preparation of substantially pure intermediate of formula (IV).
Preparation method of sugar-reducing medicine dapagliflozin
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Paragraph 0050; 0069-0071, (2019/10/01)
The invention discloses a preparation method for hypoglycemic drugdapagliflozin. The method comprises the steps that 4-hydroxybenzaldehyde is adopted as a starting raw material, alkylation, carbonyl reduction, chlorination and alkylation reaction with asepsin, diazotization and chlorination are performed to obtain a dapagliflozinmidbody 5-bromo-2-chloro-4'-ethyoxyl diphenylmethane, then, the midbody and 2,3,4,6-tetra-O-trimethyl silicone-D-glucolactone are subjected to condensation, etherification and methoxyl removal to obtain the hypoglycemic drugdapagliflozin. The raw materials adopted by the technological path are low in price and easy to obtain, the technology can achieve industrialization easily, and the final product is high in purity; the technological path is novel, the syntheticroute is short, no risky or complex technology exists in the reactions, equipment is simple, operation is easy and convenient, and the method is suitable for industrial production.
Synthetic method of dapagliflozin
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Paragraph 0083-0085; 0087-0089; 0091-0093; 0095-0097, (2019/03/24)
Disclosed is a synthesis method of dapagliflozin. The method includes providing a microreactor having at least 4 reaction units in series, delivering a 5-bromo-2-chloro-4'-ethoxydiphenylmethane solution and an alkyllithium solution into a first reaction unit and controlling the reaction temperature in the first reaction unit to be -5 to -40 DEG C; after the reaction is completed, making a reactionsolution flow into a second reaction unit, and delivering trimethylsilyl protected gluconolactone or a solution thereof to the second reaction unit; after the reaction is completed, making a reactionsolution flow into a third reaction unit and delivering a mixed solution of methanol and methane sulfonic acid to the third reaction unit; making a reaction solution flow into a fourth reaction unitafter the reaction is completed and delivering a mixed solution of boron trifluoride diethyl etherate and Triethylsilane into the fourth reaction unit.